Abstract
Correlations between Anatomy and Physiology on one side, Pathology of the wall and of the organs on the other are not well developed. It’s common clinical observation in our countries that myocardial infarction concerns younger people and cerebral infarction older people. We also know that different risk factors may be at the basis of these age difference or different pathological lesions at arterial wall level or even different structural and functional characteristics of these arterial districts.
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References
Altschul, R., 1954, “Endothelium, its development, morphology, function and pathology”,Mac-Millan Co., New York
Antonini, F.M. and Weber, G., 1951, Fosfatasi specifiche (5-nucleo- tidasi, ATP-pirofosfatasi) e fosfatasi aspecifica nella parete arteriosa normale, nell’arteriosclerosi umana, nell’arteriopatia speriraentale adrenalinica, Arch.“De Vecchi”, 14: 985
Amstrong, M.L., Peterson, R.E., Hoak, J.C., Megan, M.B., Cheng, F.H., and Clarke, W.R., 1980, Arterial platelet accumulation in experimental hypercholesterolemia, Atherosclerosis, 36: 89
Aschoff, L., 1924, Atherosclerosis, in “Lectures in Pathology”, Hoeber, New York
Becker, C.G. and Harpel, P.C., 1976, α2-macroglobulin on human vascular endothelium, J.Exp.Med., 144: 1
Bell, F.P.,Adamson,I.L.,and Schwartz, C.J., 1974a, Aortic endothelial permeability to albumina. Focal and regional patterns to uptake and transmural distribution of 131I-albumin in the young pig, Exp.Mol.Path., 20: 57
Bell, F.P., Gallus, A.S.,and Schwartz, C.J., 1974b, Focal and regional patterns of uptake and the transmural distribution of 131I-fibrinogen in the pig aorta in vivo, Exp.Mol.Path., 20: 281
Bell, F.P., Somer, J.B., Craig, I.H., and Schwartz, C.J., 1972, Patterns of aortic Evans blue uptake in vivo and in vitro, Atherosclerosis, 16: 369
Blanchette-Mackie, E.J.,and Scow, R., 1971, Sites of lipoprotein lipase activity in adipose tissue perfused with chylomicrons, J.Cell Biol., 51: 1
Buck, R.C., 1979a, Contact guidance in the subendothelial space. Repair of rat aorta in vitro, Exp.Mol.Path., 31: 275
Buck, R.C., 1979b, The longitudinal orientation of structures in the subendothelial space of rat aorta, Am.J.Anat., 156: 1
Buonassisi, V. and Venter, J.C., 1976, Hormones and neurotransmitter receptors in an established vascular endothelial cell line, Proc.Natl.Acad.Sci.(USA), 73: 1612
Buss, H., Schneider, J., and Hollweg, H.G., 1979, The endothelial surface of large veins of rabbits: scanning electron microscopic observations, Path.Res.Pract., 165: 392
Caplan, B.A. and Schwartz, C.J., 1973, Increased endothelial cell turnover in areas of in vivo Evans blue uptake in the pig aorta, Atherosclerosis, 17: 401
Christensen, B.C., Chemnitz, J., Tkocz, J., and Kim, C.M., 1979a, Repair in raterial tissue. I. Endothelial regrcwth.Subendothelial tissue changes and permeability in the healing rabbit thoracic aorta, Acta Path.Microbiol.Scand. Section A, 87: 265
Christensen, B.C., Chemnitz, J., Tkocz, J., and Kim, C.M., 1979b, Repair in arterial tissue.II. Connective tissue changes following an embolectomy catheter lesion. The importance of the endothelial cells to repair and regeneration, Acta Path.Microbiol. Scand. Section A, 87: 275
Constantinides, P., 1965, “Experimental Atherosclerosis”, Elsevier, Amsterdam
Davies, P.F. and Ross, R., 1978, Mediation of pinocytosis in cultured arterial smooth muscle and endothelial cells by platelet-derived growth factor, J.Cell Biol., 79: 663
Davies, P.F., Seldom, S.C., and Schwartz, S.M., 1979, Enhanced rates of fluid pinocytosis during exponential growth and monolayer regeneration by cultured arterial endothelial cells, J. Cell Phys., in press
Dicorleto, P. and Zilversmit, D.B., 1975, Lipoprotein lipase activity in bovine aorta, Proc.Soc.Exp.Biol.Med., 148: 1101
Dock, W., 1946, The predilection of atherosclerosis for the coronar yarteries, J.Am.Med.Assn., 131: 865
Falcone, D.J., Hajjar, D.P., and Minick, C.R., 1980, Enhancement of cholesterol and cholesteryl ester accumulation in re-endothelialized aorta, Am.J.Path., 99: 81
Fielding, C.J., Vlodavsky, I., Fielding, P.E., and Gospodarowicz, D., 1979, Characteristics of chylomicron binding and lipid uptake by endothelial cells in culture, J.Biol.Chem., 254: 8861
Fielding, P.E., Vlodavsky, I., Gospodarowicz, D., and Fielding, C.J., 1979, Effect of contact inhibition on the regulation of cholesterol metabolism in cultured vascular endothelial cells, J.Biol. Chem., 254: 749
Fuster, V., Bowie, E.J.W., Josa, M., Kaye, M.P., and Fass, D.N., 1979, Atherosclerosis in normal and Von Willebrand pigs: cross-aortic transplantation studies, VII International Congress Thromb. Haem., London, July 20, Comm. 1018- p. 425
Gaidusek, C., Dicorleto, P. Ross, R., and Schwartz, S.M., 1980, An endothelial cell-derived growth factor, J.Cell Biol., 85: 467
Geer, J.C. and Haust, M.D., 1972, Smooth muscle cells in atheroscle-rosis, in “Monographs on Atherosclerosis”, O.J. Pollack, H.S. Simms and J.E. Kirk,eds., Springer Karger, Basel-Munchen-Paris- London-New York-Sidney
Gerrity, R.G., Naito, H.K., Richardson, M., and Schwartz, C.J., 1979, Dietary induced atherogenesis in swine: morphology of the intima in prelesion stages, Am.J.Pathol., 95: 775
Gerrity, R.G., Richardson, M., Caplan, B.A., Cade, J.F., Hirsh, J., and Schwartz, C.J., 1976, Endotoxin-induced vascular endothelial injury and repair. II. Focal injury, en face morphology, H thy-midine uptake and circulating endothelial cells in the dog, Exp.Mol.Path., 24: 59
Gerrity, R.G., Richardson, M., Somer, G.B., Bell, F.P., and Schwartz, C.J., 1977, Endothelial cell morphology in areas of in vivo Evans blue uptake in the aorta of young pigs. Part 2.Ultrastructure of the intima in areas of differing permeability to protein, Am.J.Path., 89: 313
Gibofsky, A., Jaffe, E.A., Fotino, M., and Becker, C.G., 1975, The identification of HL-A antigens on fresh and cultured human endothelial cells, J.Immunol., 115: 730
Gillman, T., 1967, Possible significance of arterial hyperplasia or growth followed by involution in the genesis of arterial degeneratory disease, in “Le rôle de la paroi arterielle dans 1’atherogenese”, L. Scebat,ed., Paris
Gimbrone, M.A., 1980, Endothelial dysfunction and the pathogenesis of atherosclerosis, in “Atherosclerosis V”,A.M. Gotto, L.C. Smith and B. Alleh,eds., Springer Verlag, New York-Heidelberg- Berlin
Gimbrone, M.A. and Alexander, R.W., 1977, Insulin receptors in cultured human vascular endothelial cells, Circulation, 55: 209
Goldberg, I.D., Stemerman, M.B., Ransil, B.J., and Fuhro, R.L., 1980, In vivo aortic muscle cell growth kinetics.Differences between thoracic and abdominal segments after intimal injury in the rabbit, Circulation Res., 47: 182
Gospodarowicz, D., 1980, Interaction of LDL with the vascular endo-thelium, Second International Austrian Atherosclerosis Conf., Vienna 7–12 April(Abstract presented but not read)
Hadjiisky, P., Jurukova, Z., Renais, J.,and Scebat, L., 1978, Segmental differences in morphogenetic activity of arterial smooth muscle cells. Histochemical and radioautographic studies, Connective Tissue Res., 6: 73
Hadjiisky, P., Renais, J., and Scebat, L., 1974, Etude comparativ des enzymes aortiques de rat (atheroresistant) et de lapin (atherosensible), Bull.Assoc.Anat., 58: 571
Haley, N.J., Shio, H., and Fowler, S., 1977, Characterization of lipid-laden aortic cells from cholesterol-fed rabbits.I. Resolution of aortic cell populations by Metrizamide density gradient centrifugation, Lab.Invest., 37: 287
Haust, M.D., 1980, Milieu and function of arterial wall. The clues to unique reactivity, in “Atherosclerosis V”, A.M.Gotto, L.C. Smith and B. Allen,eds., Springer Verlag, New York-Heidelberg-Berlin
Haust, M.D., 1977, Arterial endothelium and its potential, in “Atherosclerosis. Metabolic, morphologic and clinical aspects”, Adv. in Exp.Med.Biol., G.W. Manning and M.D. Haust,eds., Plenum Press, New York-London
Helin, P., Lorenzen, I., Garbasch, C., and Matthiesen, M.E., 1969, Relative immunity to atherosclerosis in rabbits during the hair-shedding period, J.Arterioscl.Res., 10: 359
Huttner, I. and Peters, H., 1978, Heterogeneity of cell junctions in rat aortic endothelium: a freeze fracture study, J.Ultrastructure Res., 64: 303
Jaffe, E.A., Nachman, R.L., Becker, C.G., and Minick, C.R., 1973, Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria, J.Clin. Invest., 52: 2745
Jellinek, H., 1974, “Arterial lesions and arteriosclerosis”, Akad. Kiadò, Budapest
Joris, I. and Majno, G., 1974, Cellular break down within the arterial wall, Virchows Arch.A Path.Anat.Histol., 364: 111
Joris, I., Stetz, E., and Majno, G., 1979, Lymphocytes and monocytes in the aortic intima. An electron microscopic study in the rat, Atherosclerosis, 34: 221
Jorgensen, L., Packham, M.A., Rowsell, H.C., and Mustard, J.P.,1972, Deposition of formed elements of blood in the intima and signs of intimai injury in the aorta of rabbit, pig and man, Lab. Invest., 27: 341
Kibria, G., Heath, D., Smith, P., and Biggar, R., 1980, Pulmonary endothelial pavement patterns, Thorax, 35: 186
Limas, C., Westrum, B.,,and Limas, C.J., 1980, The evolution of vascular changes in the spontaneously hypertensive rats, Am.J.Path., 98: 357
Magnani, B. and Coccheri, S., 1960, Sulla patogenesi della ateromasia dietetica nel coniglio: significato dei fenomeri di alterata permeabilità vascolare, Giorn.Clin.Med., 41: 1103
Mason, R.G. and Balis, J.U., 1980, Pathology of the endothelium, in “Pathobiology of cell membranes.II.”, B.F. Trump and A.U. Arstila, eds.,Academic Press, New York-London-Toronto-Sidney-San Francisco
Mc Mahan, C.A., Mc Gill, H.C., and Wigodsky, H.S., 1978, Optimizing selection of sites for tissue blocks from arteries for microscopic evaluation, Exp.Mol.Path., 28: 129
Minick, C.R., Stemerman, M.B., and Insull, W.Jr., 1977, Effect of regenerated endothelium on lipid accumulation in the arterial wall, Proc.Natl.Acad.Sei.(USA), 74: 1724
Moares, J.R. and Stastny, P., 1977, A new antigen system expressed in human endothelial cells, J.Clin.Invest., 60: 449
Nelson, E., Gertz, S.D., Forbes, M.S., Rennels, M.L., Heald, F.P., Kahn, M.A., Farber, T.M., Miller, E., Husain, M.M., and Earl, F.L., 1976, Endothelial lesion in the aorta of egg yolk-fed miniature swine: a study by scanning and transmission electron microscopy, Exp.Mol.Path., 25: 208
Olivecrona, T., Bengtsson, G., Hook, M., and Luidohl, U., 1976, Physiologic implications of the interaction between lipoprotein lipase and some sulfated glycosaminoglycans, in “Lipoprotein metabolism”, H. Greten,ed., Springer Verlag, Berlin
Oxlund, H., Helin, P., and Lorenzen, I., 1979, Seasonal variations in the biophysical properties of rabbit aorta and its susceptibility to atherosclerosis, Atherosclerosis, 32: 397
Payling-Wright, H., 1971, Areas of mitosis in aortic endothelium of Guinea-pigs, J.Path., 105: 65
Pelikan, P. Gimbrone, M.A., and Cotran, R.S., 1979, Distribution and movement of anionic cell surface sites in cultured human vascular endothelial cells, Atherosclerosis, 32: 69
Richardson, M. and Moore, S., 1980, Preparation of large, curved biological surfaces for scanning electron microscopy, Artery, 6: 409
Ross, R. and Glomset, J.A., 1976, The pathogenesis of atherosclerosis, New Engl.J.Med., 295: 369
Ryan, U.S., Ryan, J.W., Whitaker, C., and Chiu, A., 1976, Localization of angiotensin converting enzyme (kinase II), Part 2. Immunocytochemistry and immunofuorescence, Tissue and Cell, 8: 125
Scott, R.F., Thomas, W.A., Reiner, J.M., and Florentin, R.A., 1979, Population dynamics of arterial cell during atherogenesis. IX. Similarity of endothelium cells loss over intimal smooth muscle cell masses (cushions) in aortas of swine fed normolipidemic diets for 60 days, Exp.Mol.Path., 31: 145
Simionescu, M., 1977, The morphologic basis of normal endothelium permeability; intercellular pathways, in “Atherosclerosis. Metabolic, morphologic and clinical aspects”, Adv. in Exp.Med. Biol.,G.W. Manning and M.D. Haust,eds., Plenum Press, New York- London
Simionescu, M., 1980, The cell membrane of vascular endothelium as revealed by freeze-fracture technique, Second International Austrian Atherosclerosis Conference, Vienna 7–12 April
Simionescu, M., Simionescu, N., and Palade, G.E., 1976, Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins, J.Cell Biol., 68: 705
Simionescu, N., 1980, Studies on the biochemistry of cell surface of capillary endothelium, Second International Austrian Atherosclerosis Conference, Vienna 7–12 April
Stary, H., 1980, The role of macrophages in progression and regression of primate atherosclerosis, Second International Austrian Athero-sclerosis Conference, Vienna 7–12 April
Stebhens, W.E., 1960, Focal intimal proliferation in the cerebral arteries, Am.J.Path., 36: 289
Stein, O., Chajek, T., and Stein, Y., 1976, Ultrastructural localization of Concanavalin A in the perfused rat heart, Lab.Invest., 35: 103
Stein, O. and Stein, Y., 1976, High density lipoproteins reduce the uptake of low density lipoproteins by human endothelial cells in culture, Biochem.Biophys.Acta, 431: 449
Stout, L.C. and Thorpe, L.W., 1980, Histology of normal aortas in non-human primates with emphasis on diffuse intimal thickening ( DIT ), Atherosclerosis, 35: 165
Tokes, Z.A. and Sorgente, N., 1976, Cell surface associated and released proteolytic activities of bovine aorta endothelial cells, Biochem.Biophys.Res.Comm., 73: 965
Toledo, O.M.S. and Mourao, P.A.S., 1980, Sulfated glycosaminoglycans in normal aortic wall of different mammals, Artery, 6: 341
Velican, D. and Velican, C., 1978, Human coronary arteries.II.Branching anatomical pattern and arterial wall microarchitecture, Acta Anat., 100: 258
Velican, D. and Velican, C., 1980, Comparative study on age-related changes and atherosclerotic involvement of the coronary arteries of male and female subjects up to 40 years old, in press
Vlodavsky, I., Fielding, P.E., Fielding, C.J., and Gospodarowicz, O., 1978, Role of contact inhibition in the regulation of receptor- mediated uptake of low-density lipoprotein in cultured vascular endothelial cells, Proc.Natl.Acad.Sci.(USA), 75: 356
Walton, K.W., 1980, Atherogenic factors intrinsic to the artery wall, in “Atherosclerosis V”, A.M. Gotto, L.C. Smith and B. Allen,eds., Springer Verlag, New York-Heidelberg-Berlin
Weber, G., 1977, The influence of hypercholesterolemia upon endothelial glycocalyx, in “Atherosclerosis. Metabolic, morphologic and clinical aspects”, Adv.Exp.Med.Biol., G.W. Manning and M.D. Haust, eds., Plenum Press, New York-London
Weber, G., Fabbrini, P., Barbaro, A., and Resi, L., 1.1972, Reattività della Concanavalina A sull’endotelio aortico di coniglio nella norma e nelle prime fasi dell’aterogenesi sperimentale.(Osservazioni preliminari in microscopia elettronica a trasmissione), Boll.Soc.It.Biol.Sper., 48: 1009
Weber, G., Fabbrini, P., and Resi, L., 1973, On the presence of a Concanavalin A reactive coat over the endothelial aortic surface and its modifications during early experimental cholesterol atherogenesis in rabbits, Virchows Arch.Abt.A Path.Anat., 359: 299
Weber, G., Fabbrini, P., Resi, L. Jones, R., Vesselinovitch, D., and Wissler, R.W., 1977, Regression of atherosclerotic lesions in Rhesus monkey aortas after regression diet. Scanning and transmission electron microscope observations of the endothelium, Atherosclerosis, 26: 535
Weber, G., Fabbrini, P., Resi, L., Pierli, C., and Tanganelli, P., 1978, Regeneration of endothelial cells, in “International Conference on Atherosclerosis”, L.A. Carlson, R. Paoletti, C.R. Sirtori and G. Weber,eds., Raven Press, New York
Weber, G., Fabbrini, P., Resi, L., Sforza, V., and Tanganelli, P., 1980, “Lesioni” e “disfunzione” delle cellule endoteliali nella aterogenesi sperimentale e nell’ateroregressione, Arch. “De Vecchi”, in press
Weber, G., Losi, M., Toti, P., and Vatti, R., 1978, Sulla presenza di cellule simil-endoteliali circolanti nel sangue arterioso periferico di conigli a dieta ipercolesterolica, Giorn.Arterioscl., 3: 203
Weber, G., Losi, M., Toti, P., and Vatti, R., 1979, Circulating endothelial-like cells in arterial peripheral blood of hyper-cholesterolemic rabbits, Artery, 5: 29
Wissler, R.W., 1980, The artery wall and the pathogenesis of progressive atherosclerosis, in “Atherosclerosis V”, A.M. Gotto, L.C. Smith and B. Allen,eds., Springer Verlag, New York-Heidel-berg-Berlin
Wolf, S. and Werthessen, N.T., 1975, “The smooth muscle of the artery”, Adv.Exp.Med.Biol., Plenum Press, New York-London
Zemplenyi, T., 1968, “Enzyme biochemistry of the arterial wall”, Lloyd-Luke Ltd., London
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Weber, G. (1982). Morphology and Physiology of the Arterial Wall. In: Born, G.R.V., Catapano, A.L., Paoletti, R. (eds) Factors in Formation and Regression of the Atherosclerotic Plaque. NATO Advanced Study Institutes Series, vol 51. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4268-7_1
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