Abstract
The recognition of mRNA and its binding to ribosomes are generally considered to be of key importance to translational control. That is, the decision whether a given mRNA species will be translated during cell growth, differentiation or virus infection is largely determined at initiation. Once bound to ribosomes, the mRNA will generally be translated completely, as polypeptide chain extension and completion ordinarily do not limit protein synthesis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Nakashima, K., Darzynkiewicz, E. and Shatkin, A. J. (1980), Nature, London, 286, 226–230.
Shine, J. and Dalgarno, L. (1974), Proc. Nat. Acad. Sci. U.S.A. 71, 1342–1346.
Hagenbuchle, O., Santer, M., Steitz, J. A. and Mans, R. J. (1978), Cell 13, 551–563.
Kozak, M. (1978), Cell 15, 1109–1123.
Klein, W. M., Nolan, C., Lazar, J. M., and Clark, J. M. (1972), Biochemistry 11, 2009–2014.
Trachsel, H., Erni, B., Schreier, M. and Staehelin, T. (1977), J. Mol. Biol. 116, 755–767.
Benne, R. and Hershey, J. (1978), J. Biol. Chem. 253, 3078–3087.
Benne, R., Brown-Luedi, M. and Hershey, J. (1979), Methods in Enzymol. 60, 15–35.
Thompson, H. A., Sadnik, I., Scheinbuks, J. and Moldave, K. (1977), Biochemistry 16, 2221–2230.
Kaempfer, R. (1972), J. Mol. Biol. 71, 503–598.
Dettman, G.L., and Stanley, W.M., Jr. (1972), Biochim. Biophys. Acta 287, 124–133.
Levin, D. M., Kyner, D. and Acs, G. (1973), Proc. Nat. Acad. Sei. U.S.A. 70, 41–45.
Schreier, M.H. and Staehelin, T. (1973), Nature, London, New Biol. 242, 35–38.
Darnbrough, C. M., Legon, S., Hunt, T. and Jackson, R. J. (1973), J. Mol. Biol. 76, 379–403.
Sonenberg, N., Morgan, M.A., Testa, D., Colonno, R.J. and Shatkin, A.J. (1979), Nuc. Acids Res. 7, 15–29. 1
Kaempfer, R. (1979), Methods in Enzymology 60, 380–392.
Kaempfer, R. (1979), Biochim. Biophys. Res. Commun. 61, 591–597.
Hellerman, J.G. and Shafritz, D.A. (1975), Proc. Nat. Acad. Sci, U.S.A. 72, 1021–1025.
Barrieux, A. and Rosenfeld, M.G. (1977), J. Biol. Chem. 252, 3843–3847.
Barrieux, A. and Rosenfeld, M.G. (1978), J. Biol. Chem. 253, 6311–6315.
Kaempfer, R., Hollender, R., Abrams, W.R. and Israeli, R. (1978), Proc. Nat. Acad. Sei. U.S.A. 75, 209–213.
Kaempfer, R., Hollender, R., Soreq, H. and Nudel, U. (1979), Eur. J. Biochem. 94 591–600.
Rosen, H. and Kaempfer, R. (1979), Biochem. Biophys. Res. Commun. 91, 449–455.
Kaempfer, R., Van Emmelo, J. and Fiers, W. (1981), Proc. Nat. Acad. Sei. U.S.A., in press.
Kaempfer, R., Rosen, H. and Israeli, R. (1978), Proc. Nat. Acad. Sci. U.S.A. 75, 650–654.
Lesnaw, A. and Reichmann, M.E. (1968), J. Mol. Biol. 38, 59–73.
Browning, K.S., Leung, D.W. and Clark, J.M., Jr. (1980), Biochemistry 19, 2276–2282.
Smith, R.E. and Clark, J.M., Jr. (1979), Biochemistry 18, 1366–1371.
Kaempfer, R. (1981), in Protein Biosynthesis in Eukaryotes (R. Perez-Bercoff, Ed.), Plenum Press, New York and London.
Di Segni, G., Rosen, H. and Kaempfer, R. (1979), Biochemistry 18, 2847–2854.
Schreier, M., Staehelin, T., Gesteland, R. and Spahr, P. (1973), J. Mol. Biol. 75, 575–578.
Kaempfer, R. and Kaufman, J. (1973), Proc. Nat. Acad. Sci. U.S.A. 70, 1222–1226.
Rosen, H., Knoller, S. and Kaempfer, R. (1980), submitted.
Ysebaert, M., Van Emmelo, J. and Fiers, W. (1980), J. Mol. Biol. 143, 273–287.
Rosenfeld, M.G. and Barrieux, A. (1979), Methods in Enzymology 60, 392–401.
Rosenfeld, M.G. and Barrieux, A. (1977), Biochemistry 16, 514–518.
Sonenberg, N., Rupprecht, K.M., Hecht, S.M., and Shatkin, A.J. (1979), Proc. Nat. Acad. Sci. U.S.A. 76, 4345–4349.
Kabat, D. and Chappell, M. (1977), J. Biol. Chem. 252, 2684–2690.
Golini, F., Thach, S.S., Birge, C.H., Safer, B., Merrick, W.C. and Thach, R.E. (1976), Proc. Nat. Acad. Sei. U.S.A. 73, 3040–3044.
Baglioni, C., Simili, M. and Shafritz, D.A. (1978), Nature, London, 275, 240–243.
Pavlakis, G.N., Lockard, R.E., Vanvakopoulos, N., Rieser, L., Raj-Bhandary, U.L., Vourmakis, J.M. (1980), Cell 19, 91–102.
Kozak, M. (1980), Cell 19, 79–90.
Kaempfer, R., Israeli, R., Rosen, H., Knoller, S., Zilberstein, A., Schmidt, A. and Revel, M. (1979), Virology 99, 170–173.
Perez-Bercoff, R. and Kempfer, R. (1981), submitted.
Weber, L.A., Hickey, E.D., Maroney, P.A. and Baglioni, C. (1977), J. Biol. Chem. 252, 4007–4010
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1982 Plenum Press, New York
About this chapter
Cite this chapter
Kaempfer, R. (1982). Initiation Factor/mRNA Interactions and mRNA Recognition. In: Pérez-Bercoff, R. (eds) Protein Biosynthesis in Eukaryotes. NATO Advanced Study Institutes Series, vol 41. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4124-6_9
Download citation
DOI: https://doi.org/10.1007/978-1-4684-4124-6_9
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-4126-0
Online ISBN: 978-1-4684-4124-6
eBook Packages: Springer Book Archive