Abstract
Bordetellapertussis (pertussis) is a gram negative coccobacillus and was identified to be the etiological agent of “whooping cough” by Bordet and Gengou in 1906 (7). Much of the early work on pertussis was concerned with identifying the protective antigens so that an effective vaccine could be produced for humans. A whole cell vaccine was introduced in the 1940’s and today is administered world-wide to millions of infants (31). The present vaccine appears to be of major benefit in preventing infant whooping cough, but because of its associated toxicity recent emphasis has been placed on developing a non-whole cell, more highly purified vaccine (40).
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References
Axline, S., and Reaven, E., 1974, Inhibition of phagocytosis and plasma membrane mobility of the cultivated macrophage by cytochalasin B. J. Cell Biol. 62: 647.
Barrett, A., and Heath, M., 1977, Lysosomal Enzymes, p. 19–145. In J. Dingle (ed.), Lysosomes a laboratory handbook. North Holland Publishing Co., New York.
Bianco, C., 1976, Methods for the study of macrophage Fc and C3 receptprs, p. 407–415. In B.R. Bloom and J. R. David (eds.), In vitro methods in cell-mediated and tumor immunity. Academic Press Inc., New York.
Bianco, C., Eden, A., and Cohn, Z., 1976, The induction of macrophage spreading: role of coagulation factors and the complement system. J. Exp. Med. 144: 1531.
Bianco, C., Griffin, F., and Silverstein, S., 1975, Studies of the macrophage complement receptor. J. Exp. Med. 141: 1278.
Blanden, R., 1968, Modification of macrophage function. J. Reticuloendothel. Soc. 5; 179.
Bordet, J., and Genous, O., 1906, Le microbe de la coqueluche. Ann. Inst. Pasteur 20: 731.
Burley-Rosset, M., Florentin, I., Khalil, A., and Mathe, G.,1976, Nonspecific macrophage activation by systemic adjuvants. Int. Archs. Allergy Appl. Immun. 51: 594.
Cohn, Z., and Benson, B., 1965, The differentiation of mononuclear phagocytes. J. Exp. Med. 121: 153.
David, J., and Remold, H., 1976, Macrophage activation by lymphocyte mediators and studies on the interaction of macrophage inhibition factor (MIF) with its target cell, p. 401–426. In D. S. Nelson (ed.) Immunobiology of the Macrophage. Academic Press, Inc., New York.
Dresser, D., 1972, The role of T cells and adjuvant in the immune response of mice to foreign erythrocytes. Eur. J. Immunol. 2: 50.
Dresser, D., Wortis, H., and Anderson, H., 1970, The effect of pertussis vaccine on the immune response of mice to sheep red blood cells. Clin. Exp. Immunol. 7: 817.
Edelson, P., and Erb, C., 1978, Biochemical and functional characteristics of the plasma membrane of macrophages from BCG-infected mice. J. Immunol. 120: 1532.
Finger, H., Heymer, B., Wirsing, C., Emmerling, P., and Hof, H., 1978, Riversion of dextran sulfate-induced loss of antibacterial resistance by Bordetella pertussis. Infect. Immun. 19: 950.
Fishel, C., Halkias, D., Klein, T., and Szentivanyi, A., 1976, Characteristics of cells present in peritoneal fluids of mice injected intraperitoneally with Bordetella pertussis. Infect. Immun. 13: 263.
Giovanella, B., and Stehlin, J., 1973, Heterotransplantation of human malignant tumors in “nude” thymusless mice. I. Breeding and mainteance of “nude” mice. J. Nat. Cancer Inst. 51: 615.
Götze, O., Bianco, C., and Cohn, Z., 1979, The induction of macrophage spreading by factor B of the properdin system. J. Exp. Med. 149: 372.
Greenberg, L., and Fleming, D., 1947, Increased efficiency of diptheria toxoid when combined with pertussis vaccine. Cand. J. Pub. Health. 38: 279.
Hamaoka, T., and Katz, D., 1973, Cellular site of action of various adjuvants in antibody responses to hapten-carrier conjugates. J. Cell Biol. 11: 1554.
Halentjaris, T., Lombardi, P., and Glasgow, L., 1976, Effect of cytochalasin B on the adhesion of mouse peritoneal macro-phages. J. Cell Biol. 69: 407.
Ho, M., Kong, A., and Morse, S., 1979, The in vitro effects of Bordetella pertussislymphocytosis-promoting factor on murine lymphocytes. J. Exp. Med. 149: 1001.
Hof, H., Emmerling, P., Finger, H., and Wirsing, C., 1978, In-fluence of killed Bordetella pertussis cells on the resistance against infection with Listeria monocytogenes. 261. Bakt. Hyg. I. Abt. Orig. A 240: 208.
Kirchner, H., Scott, M., Hirt, H., and Münk, K., 1978, Protection of mice against viral infection by Corynebacterium parvum and Bordetella pertussis. J. Gen. Virol. 41: 97.
Klein, T., Pross, S., and Benjamin, W., 1978, Characterization of mouse peritoneal exudate and associated leukocyte adherence inhibitory activity after intraperitoneal injection of either Bordetella pertussis or Corynebacterium parvum vaccines. Infect. Immun. 22: 778.
Kong, A., and Morse, S., 1976, The effect of Bordetella pertussis on the antibody response in mice to type III pneumococcal poly-saccharide. J. Immunol. 116: 989.
Levine, S., and Sowinski, R., 1972, Inhibition of macrophage response to brain injury. Am. J. Pathol. 67: 349.
Morland, B., and Morland, J., 1978, Selective induction of lysosomal enzyme activities in mouse peritoneal macrophages. J. Reticuloendothel. Soc. 23: 469.
Morse, S., 1965, Studies on the lymphocytosis induced in mice by Bordetella pertussis. J. Exp. Med. 121: 49.
Morse, S., 1976, Biologically active components and properties of Bordetella pertussis. Adv. Appl. Microbiol. 20: 9.
Mota, I., and Peixoto, J., 1966, A skin-sensitizing and thermo- labile antibody in the mouse. Life Sciences 5: 1723.
Munoz, J., and Bergman R., 1977, Bordetella pertussis immuno-logical and other biological activities. Marcel Dekker, Inc. New York.
Murgo, A., and Athanassiades, T., 1975, Studies on the adjuvant effect of Bordetella pertussis vaccine to sheep erythrocytes in the mouse. 115: 928.
North, R., 1969, Cellular kinetics associated with the development of acquired cellular resistance. J. Exp. Med. 130: 299.
Parfentjev, I., and Goodline, M., 1948, Histamine shock in mice sensitized with Hemophilus pertussis vaccine. J. Pharmacol. Exptl. Therap. 92: 411.
Suko, M., Ogita, T., Okudaira, H., and Horiuchi, Y., 1977, Preferential enhancement of IgE antibody formation by Bordetella pertussis. Int. Archs. Allergy Appl. Immun. 54: 329.
Unanue, E., Askonas, B., and Allison, A., 1969, A role of macro-phages in the stimulation of immune responses by adjuvants. J. Immunol. 103: 71.
Wilkinson, P., 1976, Cell-membrane activation of macrophage function, p. 41–48. In G. Mathe, I. Florentin, M. Simmler (eds.), Recent results in cancer research, vol. 56. Springer- Verlag, New York.
Wilkinson, P., 1976, Cellular and molecular aspects of Chemotaxis of macrophages and monocytes, p. 349–365. In D. Nelson (ed.), Immunobiology of the macrophage. Academic Press, New York.
Yagel, S., Gallily, R., and Weiss, D., 1975, Effect of treatment with the MER fraction of tubercle bacilli on hydrolytic lysosomal enzyme activity of mouse peritoneal macrophages. Cell. Immunol. 19: 381.
Zakharova, M., 1979, Theortetical outlines on the preparation of a noncellular pertussis vaccine. In C. R. Manclark and J. C. Hill (eds.), International Symposium on Pertussis, pp. 320. DHEW Publication No. (NIH) 79–1830. Washington, DC.
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Klein, T., Benjamin, W., Winters, A., Friedman, H. (1981). Pertussis Induced Immunomodulation. In: Friedman, H., Klein, T.W., Szentivanyi, A. (eds) Immunomodulation by Bacteria and Their Products. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4115-4_16
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DOI: https://doi.org/10.1007/978-1-4684-4115-4_16
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