Skip to main content
SpringerLink
Log in

Molecular Aspects of Synaptic Transmission — The Role of Cyclic Nucleotides and Protein Phosphorylation

  • Chapter
Investigation of Brain Function

Part of the book series: Ettore Majorana International Science Series ((EMISS,volume 7))

  • 65 Accesses

Abstract

Considered broadly synaptic transmission involves a series of molecular events starting with the synthesis of neurotransmitter and ending with the modification of the activity of the post-synaptic cell. Knowledge of the detail of the component processes is patchy and is clearly complicated by the diversity of the molecules now known to function as neurotransmitters.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Briley, M.S. and Changeux, J.P., (1977), Int. Rev. Neurobiol., 20. 31–63.

    Article  Google Scholar 

  2. Dolly, J.O., (1979), Int. Rev. Biochem., 26, 257–309.

    Google Scholar 

  3. Birdsall, N.J.M., Burgen, A.S.V. and Hulme, E.C., (1979), Brit. J. Pharmacol., 66, 337–342

    Google Scholar 

  4. Daly, J.W., (1977), Int. Rev. Neurobiol., 20, 105–168.

    Article  Google Scholar 

  5. Kebabian, J.W., (1977), Adv. Cyc. Nuc. Res., 8, 421–508.

    Google Scholar 

  6. Nathanson, J.A., (1977), Physiol. Reviews, 57, 157–256.

    Google Scholar 

  7. Williams M. and Rodnight, R., (1977), Prog. Neurobiol., 8, 259–269. Raven Press, New York.

    Article  Google Scholar 

  8. Greengard, P. (1978), Cyclic Nucleotides, Phosphorylated Proteins and Neuronal Function. Raven Press, New York.

    Google Scholar 

  9. Rodnight, R., (1979), Int. Rev. Biochem., 26, 1–80.

    Google Scholar 

  10. Chan-Palay, V. and Palay, S.L., (1979), Proc. Natn. Acad. Sci. (USA), 76, 1485–1488.

    Article  Google Scholar 

  11. Panula, P. and Rechardt, L., (1979), Neuroscience, 4, 779–788.

    Article  Google Scholar 

  12. Kuik, M., Emson, P.C. and Joyce, E., (1979), Brain Res., 167, 355–365.

    Article  Google Scholar 

  13. Hirata, F., Strittmatter, W.J. and Axelrod, J., (1979), Proc. Nam. Acad. Sci. (USA), 76, 368–372.

    Article  Google Scholar 

  14. Strittmatter, W.J., Hirata, F. and Axelrod, J., (1979), Science, 204, 1205–1207.

    Article  Google Scholar 

  15. Gilman, A.G. and Ross, E.M., (1979), In: The Neurosciences Fourth Study Program, eds. F.O. Schmitt and F.G. Worden, pp. 819–829, MIT Press, Cambridge, Mass.

    Google Scholar 

  16. Levitzki, A., (1979), Biochem. Pharmacol., 27, 2083–2088.

    Article  Google Scholar 

  17. Schlegel, W., Kempner, E.S. and Rodbell, M., (1979), J. Biol. Chem., 254, 5168–5176.

    Google Scholar 

  18. Enjalbert, A., Bourgoin, S., Hamon, M., Adrien, J. and Bochaert, J., (1978), Mol. Pharmacol., 14, 2–10.

    Google Scholar 

  19. Kanof, P.D. and Greengard, P., (1979), J. Pharmacol. Expt. Ther., 209, 87–96.

    Google Scholar 

  20. Premont, J., Tassin, J.P., Blanc, G. and Bockaert, J., (1979), In: Physiological and Regulatory Functions of Adenosine and Adenine Nucleotides, edited by H.P. Baer and G.I. Drummond, pp. 259–269. Raven Press, New York.

    Google Scholar 

  21. Weiler, M., (1979), Protein Phosphorylation, Pion Ltd., London.

    Google Scholar 

  22. Forn, J. and Greetard, P., (1978), Proc. Natn. Acad. Sce. (USA), 75, 5195–5199.

    Article  Google Scholar 

  23. Dunkley, P., Holmes, H. and Rodnight, R., (1977), Biochem. J., 163. 369–378.

    Google Scholar 

  24. Jones, D.H. and Matus, A.L., (1974), Biochem. Biophys. Acta, 356, 276–287.

    Article  Google Scholar 

  25. Lohmann, S.M., Ueda, T. and Greegard, P., (1978), Proc. Natn. Acad. Sci. (USA), 75, 4037–4041.

    Article  Google Scholar 

  26. Ueda, T. and Greengard, P., (1977), F. Biol. Chem., 252, 5155–5163.

    Google Scholar 

  27. Ueda, T., Greengard, P., Berzinz, K., Cohen, R.S., Bloomberg, F., Grab, D.J. and Siekevitz, P., (1979), F. Cell Biol., 83. 308–319.

    Article  Google Scholar 

  28. Bloom, F.E., Ueda, T., Battenburg, E. and Greengard, P., (1979), Proc. Natn. Acad. Sci. (USA), 76, 5982–5986.

    Article  Google Scholar 

  29. Uno, I., Ueda, R. and Greengard, P., (1977), J. Bio. Chem., 252, 5164–5174.

    Google Scholar 

  30. Walter, U., Uno, I., Liu, A.Y-C. and Greengard, P., (1977), J. Biol. Chem., 252, 6588–6590.

    Google Scholar 

  31. Schulman, H. and Greegard, P., (1978), Proc. Natn. Acad. Sci. (USA), 75, 5432–5436.

    Article  Google Scholar 

  32. Zwiers, H., Tonnaer, J., Wiegant, V.M., Schotman, P. and Gispen, W.H., (1979), J. Neurochem., 33, 247–256.

    Article  Google Scholar 

  33. Huttner, W.R. and Greengard, P., (1979), Proc. Natn. Acad. Sci. (USA), 76, 5402–5406.

    Article  Google Scholar 

  34. Michelson, E., (1978), Science, 201, 69–71.

    Article  Google Scholar 

  35. Oeda, R.F. and Katz, M., (1976), Proc. Natn. Acad. Sci. (USA), 73, 3398–3402.

    Article  Google Scholar 

  36. Wallach, D. and Pastan, I., (1976), Biochem. Biophys. Res. Commun., 72, 859–865.

    Article  Google Scholar 

  37. Rubin, E.H. and Terendelli, J.A., (1977), J. Neurochem., 29, 43–51.

    Article  Google Scholar 

  38. Biggio, G., Brodie, B.B., Costa, E. and Guidorri, A., (1977), Proc. Natn. Acad. Sci. (USA), 74, 3592–3596.

    Article  Google Scholar 

  39. Tjornhammer, M.-L., Schwarcz R., Bartfai, T. and Fuxe, K., (1979), Brain Res., 171, 567–572.

    Article  Google Scholar 

  40. Takai, Y., Nichiyama, K., Yamamura, H. and Nichizuka, Y., (1975), J. Biol. Chem., 250, 4690–4695.

    Google Scholar 

  41. Bandle, E. and Guidotti, A., (1979), J. Neurochem., 32, 1343–1347.

    Article  Google Scholar 

  42. Yanauchi, T. and Fujisawa, H., (1979), J. Bio. Chem., 254, 503–507.

    Google Scholar 

  43. Joh, T.H., Park, D.H. and Reis, D.J., (1978), Proc. Natn. Acad. Sci. (USA), 75, 4744–4748.

    Article  Google Scholar 

  44. Weiner, N. (1980), Essays in Neurochemistry and Neuropharmacology, 4, 69–124.

    Google Scholar 

  45. Llinas, R.R., (1977), Quoted by L. Tauc, (1979). Biochem. Pharmacol., 27, 3493–3498.

    Google Scholar 

  46. Baker, P.F. and Knight, D.E., (1979), J. Physiol., 295, 80P

    Google Scholar 

  47. Libet, B., (1979), Life Sci., 24, 1043–1058.

    Article  Google Scholar 

  48. Brown, D.S., Caulfield, M.P. and Kriby, P.J., (1979), J. Physio., 290, 441–451.

    Google Scholar 

  49. Wilkening, D. and Makman, M.H., (1977), J. Neurochem., 28, 1001–1007.

    Article  Google Scholar 

  50. Kurosawa, A., Guidotti, A. and Costa, E., (1979), Mo. Pharmacol. 15, 115–130.

    Google Scholar 

  51. McIlwain, H. (1978), Prog. Neurobiol., 11, 189–203.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurochemistry, Institute of Psychiatry Maudsley Hospital, Denmark Hill, London, SE5, UK

    Richard Rodnight

Authors
  1. Richard Rodnight
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institute of Child Health, University of London, London, England

    A. W. Wilkinson

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Plenum Press, New York

About this chapter

Cite this chapter

Rodnight, R. (1981). Molecular Aspects of Synaptic Transmission — The Role of Cyclic Nucleotides and Protein Phosphorylation. In: Wilkinson, A.W. (eds) Investigation of Brain Function. Ettore Majorana International Science Series, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4043-0_12

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-4043-0_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4045-4

  • Online ISBN: 978-1-4684-4043-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation