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Fluorescent-Probe Studies of Contractile Proteins

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Cell and Muscle Motility

Abstract

The present knowledge of the mechanism of muscle contraction and cell movement at the molecular level comes from an accumulation of experimental evidence obtained using a wide variety of biochemical and biophysical techniques. In relatively recent times, the use of intrinsic and extrinsic fluorescence probes has provided useful information about the kinetic intermediates, mobility, binding, orientation, intramolecular distances, and site environment of the globular head region of the myosin molecule, both free in solution and as a part of the intact muscle “cross-bridges” that are thought to be the impellers of biological movement.

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Biophysics and The Cardiovascular Research Institute, University of California, San Francisco, California, 94143, USA

    Robert A. Mendelson

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  1. Robert A. Mendelson
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Editor information

Editors and Affiliations

  1. Baylor University Medical Research Institute, Dallas, Texas, USA

    Robert M. Dowben

  2. University of Texas Health Science Center, Dallas, Texas, USA

    Robert M. Dowben  & Jerry W. Shay  & 

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© 1982 Plenum Press, New York

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Mendelson, R.A. (1982). Fluorescent-Probe Studies of Contractile Proteins. In: Dowben, R.M., Shay, J.W. (eds) Cell and Muscle Motility. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4037-9_19

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  • DOI: https://doi.org/10.1007/978-1-4684-4037-9_19

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-4039-3

  • Online ISBN: 978-1-4684-4037-9

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