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Galactofuranosyl-Containing Lipoglycopeptide in Penicillium

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The Phytochemistry of Cell Recognition and Cell Surface Interactions

Part of the book series: Recent Advances in Phytochemistry ((RAPT,volume 15))

Abstract

Fungi secrete numerous macromolecules which are derived from a) walls, b) enzymes, and c) subcellular organelles. These macromolecules are subject to the action of lytic enzymes located in the nutrient medium. Therefore, many polymers found in media supporting fungal growth are degradation products of more complex substances. For instance, galactocarolose, a 5-O-ß-D-galactofuranosyl-containing decasaccharide, and mannocarolose, an α-D-mannopyranosyl-containing nonasaccharide, first isolated from 28-day culture filtrates of Penicillium charlesii and partially characterized in W. N. Haworth’s laboratory1, 2 have been shown to be derived from a more complex glycopeptide3–5 which first appears in the growth medium soon after formation of conidia.6 Because of the composition of the complex glycopeptide we have referred to it as a peptidophosphogalactomannan.3 The glycopeptide may be the major polysaccharide-containing substance secreted prior to general lysís of the fungus.6, 7 Peptidophosphogalactomannans and/or peptidogalactomannans have been obtained from Cladosporium werneckii,8, 9 species of Aspergillus,10–12 several species of dermatophytes from the genera of Trichophyton and Microsporum, 13, 14 Fulvia fulva (Cooke) Ciferril5 and several species of Penicilliuml0, 16, 17 and may be common constituents of many genera of fungi.

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Authors and Affiliations

  1. Department of Biochemistry College of Biological Sciences, University of Minnesota, St. Paul, Minnesota, 55108, USA

    J. E. Gander & Cynthia J. Laybourn

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  1. J. E. Gander
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  1. Institute of Biological Chemistry, Washington State University, Pullman, Washington, USA

    Frank A. Loewus  & Clarence A. Ryan  & 

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© 1981 Plenum Press, New York

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Gander, J.E., Laybourn, C.J. (1981). Galactofuranosyl-Containing Lipoglycopeptide in Penicillium. In: Loewus, F.A., Ryan, C.A. (eds) The Phytochemistry of Cell Recognition and Cell Surface Interactions. Recent Advances in Phytochemistry, vol 15. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3986-1_4

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  • DOI: https://doi.org/10.1007/978-1-4684-3986-1_4

  • Publisher Name: Springer, Boston, MA

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