Abstract
One common approach to building a model for plasmid maintenance is to identify, map and characterize the genes involved in this process. The two major features of maintenance are plasmid replication and partitioning to daughter cells. As depicted elsewhere in this text, the essential components of replication appear to be at least a fixed origin of replication (ori), one to two plasmid-specified gene products for replication (rep) and a copy number control gene (cop) that appears to exert negative control. So too, plasmid F, the classic conjugal plasmid of Escherichia coli, appears to fit this general model of replication. However, F may have a more complex genetic organization for this process than other plasmids.
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© 1981 Springer Science+Business Media New York
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Kline, B., Seelke, R., Trawick, J. (1981). Replication and Incompatibility Functions in Mini-F Plasmids. In: Levy, S.B., Clowes, R.C., Koenig, E.L. (eds) Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3983-0_30
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DOI: https://doi.org/10.1007/978-1-4684-3983-0_30
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