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Genetic Organization and Expression of Non-Conjugative Plasmids

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Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids

Abstract

Non-conjugative plasmids are plasmids that are not able to transfer themselves to other cells without the help of a conjugative system provided by the large, so-called conjugative plasmids. Non-conjugative plasmids are small plasmids. Their M.W. generally does not exceed 10 Megadaltons. Furthermore, they are multicopy plasmids; that means that they are usually present to the extend of 10-20 copies per chromosome. As all other small DNA molecules, the non-conjugative plasmids are very attractive for basic research. Over the past ten years studies on plasmids were focused on basic questions dealing with gene-function, gene-organisation, gene-expression, mechanism and control of replication, and plasmid mobilisation. And, ever since it became apparent that plasmids are a very useful tool in genetic engineering also a lot of work has been done on the construction of appropriate vector molecules.

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Author information

Authors and Affiliations

  1. Department of Genetics, Biological Laboratory De Boelelaan, 1087, Amsterdam, The Netherlands

    H. John, J. Nijkamp & Eduard Veltkamp

Authors
  1. H. John
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  2. J. Nijkamp
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  3. Eduard Veltkamp
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Editor information

Editors and Affiliations

  1. Tufts University School of Medicine, Boston, Massachusetts, USA

    Stuart B. Levy

  2. The University of Texas at Dallas, Richardson, Texas, USA

    Royston C. Clowes

  3. Universidad Nacional Pedro Henriquez Urena, Santo Domingo, Dominican Republic

    Ellen L. Koenig

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© 1981 Springer Science+Business Media New York

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John, H., Nijkamp, J., Veltkamp, E. (1981). Genetic Organization and Expression of Non-Conjugative Plasmids. In: Levy, S.B., Clowes, R.C., Koenig, E.L. (eds) Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3983-0_24

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  • DOI: https://doi.org/10.1007/978-1-4684-3983-0_24

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3985-4

  • Online ISBN: 978-1-4684-3983-0

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