Abstract
Pathogenic bacteria that cause generalized infections or meningitis invade the blood stream and are thereby distributed throughout the body. Blood, or serum, contains a number of nonspecific (complement, lysozyme, phagocytes, iron-binding proteins, etc.) and specific (antibodies, lymphocytes) agents that alone or in combination lyse, kill or prevent the growth of the majority of bacteria with which they make contact. Abilities to resist, evade or inactivate these host defences constitute major components of the virulence of invasive bacteria. At present little is known about these bacterial properties or their molecular interactions with host defences.
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References
G.K. Schoolnik, T.M. Buchanan, and K.K. Holmes, J. Clin. Invest. 58: 1163–1173 (1976).
M.S. Simberkoff, I. Ricupero, and J.J. Rahal, Jr., J. Lab. Clin. Med. 87: 206–217 (1976).
B. Björksten and B. Kaijser, Infect. Immun. 22: 308–311 (1978).
G. Archer and F.R. Fekety, J. Infect. Dis. 134: 1–7 (1976).
D.T. Durack and P.B. Beeson, Infect. Immun. 16: 213–217 (1977).
A.M. Reynard and M.E. Beck, Infect. Immun. 14: 848–850 (1976).
A. Fietta, E. Romero, and A.G. Siccardi, Infect. Immun. 18: 278–282 (1977).
P.W. Taylor and C. Hughes, Infect. Immun. 22: 10–17 (1978).
R.P. Silver and S.N. Cohen, J. Bacteriol. 110: 1082–1088 (1972).
K.N. Timmis, F. Cabello, and S.N. Cohen, Molec. Gen. Genet. 162: 121–137 (1978).
M. Achtman, B. Kusecek, and K.N. Timmis, Molec. Gen. Genet. 163: 169–179 (1978).
A. Moll, P.A. Manning, and K.N. Timmis, Infect. Immun. 28: 359–367 (1980).
P.A. Manning and M. Achtman, in_: “Bacterial Outer Membranes: Biogenesis and Functions”, M. Inouye, ed., Wiley, New York pp. 409–447 (1979).
A. Moll, F. Cabello, and K.N. Timmis, FEMS Lett. 6: 273–276 (1979).
P.A. Manning, L. Beutin, and M. Achtman, J. Bacteriol. 142: 285–294 (1980).
D. Ferrazza and S.B. Levy, J. Bacteriol. 144: 149–158 (1980).
R.T. Ogata and R.P. Levine, J. Immunol. 125: 1494–1498 (1980).
P.A. Manning, C. Echarti, and K.N. Timmis, to be submitted.
J.B. Robbins, G.H. McCracken, E.C. Gotschlich, F. Orskov, I. Orskov, and L.A. Hanson, New Eng. J. Med. 290: 1216–1220 (1974).
M. Glode, A. Sutton, R. Moxon, and J.B. Robbins, Infect. Immun. 16: 75–80 (1977).
F. Cabello in: “Plasmids of Medical, Environmental and Commercial Importance”, K.N. Timmis and A. Punier, eds., Elsevier/North Holland, Amsterdam, pp. 155–160 (1979).
R. Bortolussi, P. Ferrieri, B. Bjorksten, and P.G. Cline, Infect. Immun. 25: 293–298 (1979).
A.A. Glynn and C.J. Howard, Immunol. 18: 331–346 (1970).
W.R. McCabe, B. Kaijser, S. Oiling, M. Uwaydah, and L.A. Hanson, J. Infect. Dis. 138: 33–40 (1978).
J. Pitt, Infect. Immun. 22: 219–224 (1978).
B. Hohn and N. Hinnen, in: “Genetic Engineeri1ng, Principles and Methods”, Vol 2, J.K. Setlow and A. Hollaender, eds., Plenum, New York, pp. 169–183 (1980).
P. Gemski, A.S. Cross, and J.C. Sadoff, FEMS Lett. 9: 193–197 (1980).
M.E. Bayer, J. Gen. Microbiol. 53: 395–404 (1968).
H.W. Smith, J. Gen. Microbiol. 83: 95–111 (1974).
H.W. Smith and M.B. Huggins, J. Gen. Microbiol. 92: 335–350 (1976).
M.M. Binns, D.L. Davies, and K.G. Hardy, Nature 279: 778–781 (1979).
J.F. Hildebrandt, L.W. Mayer, S.P. Wang, and T.M. Buchanan, Infect. Immun. 20: 267–273 (1978).
J.B. Robbins, R. Schneerson, W.B. Egan, W. Vann, and D.T. Liu, in: “The Molecular Basis of Microbial Pathogenicity”, H. Smith, J.J. Skehel, and M.J. Turner, eds., Verlag Chemie, Weinheim, pp. 115–132 (1980).
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Timmis, K.N., Manning, P.A., Echarti, C., Timmis, J.K., Moll, A. (1981). Serum Resistance in E.coli . In: Levy, S.B., Clowes, R.C., Koenig, E.L. (eds) Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3983-0_14
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DOI: https://doi.org/10.1007/978-1-4684-3983-0_14
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