Abstract
In his excellent monograph, The Anatomy of Aging in Man and Animals, Andrew (1971) notes that the bewildering variety of animals regarding size, structure, way of life, and longevity may discourage gerontologists in search of common mechanisms. However, in his opinion, morphological studies suggest that senescence is not a heterogeneous accumulation of pathological lesions but a fundamental process. He further comments on the importance of unifying biological concepts, such as the cell theory and, more recently, the electron microscopic demonstration of the basic similarity of cellular organelles.
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References
Andrew, W., 1962, An electron microscope study of age changes in liver of the mouse, Am. J. Anat. 110:1.
Andrew, W., 1964, Changes in the nucleus with advancing age of the organism, Adv. Gerontol. Res. 1:87.
Andrew, W., 1971, The Anatomy of Aging in Man and Animals, Grune & Stratton, New York.
Bourne, G. H., 1961, Structural Aspects of Ageing, Hafner, New York.
Bozuck, A. N., 1972, DNA synthesis in the absence of somatic cell division associated with ageing in Drosophila subobscura, Exp. Gerontol. 7:147.
Burek, J. D., 1978, Pathology of Aging Rats, CRC Press, West Palm Beach.
Davies, I., 1974, The effect of age and diet on the ultrastructure of hymenopteran flight muscle, Exp. Gerontol. 9:215.
Dillard, C. J., and Tappel, A. L., 1973, Fluorescent products of lipid peroxidation of mitochondria and microsomes, Lipids 6:715.
Duncan, D., Nall, D., and Morales, R., 1960, Observations on the fine structure of old age pigment, J. Gerontol. 15:366.
Epstein, J., Himmelhoch, S., and Gershon, D., 1972, Studies on ageing in nematodes. III. Electron microscopical studies on age-associated cellular damage, Mech. Ageing Dev. 1:245.
Ferris, G. F., 1965, External morphology of the adult, in: Biology of Drosophila (M. Demerec, ed.), pp. 368–419, Hafner, New York.
Geary, S., and Florini, J. R., 1972, Effect of age on rate of protein synthesis in isolated perfused mouse hearts, J. Gerontol. 27:325.
Ghosh, A., Bern, H. A., Ghosh, I., and Nishioka, R. A., 1962, Nature of the inclusions in the lumbosacral neurons of birds, Anat. Rec. 143:195.
Glees, P., and Hasan, M., 1976, Lipofuscin in Neuronal Aging and Diseases, Thieme, Stuttgart.
Hackman, R. H., 1964, Chemistry of the insect cuticle, in: Physiology of Insecta (M. Rockstein, ed.), Vol. I, pp. 471–506, Academic Press, New York.
Herbener, G. H., 1976, A morphometric study of age-dependent changes in mitochondrial populations of mouse liver and heart, J. Gerontol. 31:8.
Herman, M. M., Miquel, J., and Johnson, M., 1971, Insect brain as a model for the study of aging. Agerelated changes in Drosophila melanogaster, Acta Neuropathol. 19:167.
Hess, A., 1955, The fine structure of young and old spinal ganglia, Anat. Rec. 123:399.
Hrachovec, J. P., 1969, Age changes in aminoacid incorporation by rat liver microsomes, Gerontologia 15:52.
Johnson, J. E., Jr., and Miquel, J., 1974, Fine structural changes in the lateral vestibular nucleus of aging rats, Mech. Ageing Dev. 3:203.
Johnson, J. E., Jr., and Miquel, J., 1978, Comparative electron microscopic studies of various cell types in the aging mammal, Age 1:78.
Johnson, J. E., Jr., Mehler, W. R., and Miquel, J., 1975, A fine structural study of degenerative changes in the dorsal column nuclei of aging mice. Lack of protection by vitamin E, J. Gerontol. 30:395.
Johnson, J. E., Jr., Miquel, J., Binnard, R., and Economos, A. C., 1978a, Effects of antioxidants on the liver of aging mice, Age 1:162.
Johnson, J. E., Jr., Philpott, D. E., and Miquel, J., 1978b, A study of axonal degeneration in the optic nerves of aging mice, Age 1:50.
Kanungo, M. S., Koulo, O., and Reddy, K. R., 1970, Concomitant studies on RNA and protein synthesis in tissue of rats of various ages, Exp. Gerontol. 5:161.
Kment, V. A., Leibetseder, V., and Adamiker, D., 1966a, Gerontologische Untersuchungen an Rattenle-bermitochondrien, Z. Alternsforsch. 19:241.
Kment, V. A., Leibetseder, J., and Burger, H., 1966b, Gerontologische Untersuchungen an Rattenherz-mitochondrien, Gerontologia 12:193.
Koenigsberger, I. R., 1960, On the relationship between development and aging, Gerontological Society Newsletter 7:33.
Kohn, R. R., 1971, Principles of Mammalian Aging, Prentice-Hall, Englewood Cliffs, N. J.
Kumamoto, T., and Bourne, G. H., 1963, Histochemical localization of respiratory and other hydrolytic enzymes in neuronal lipopigment (lipofuscin) in old guinea pigs, Acta Histochem. 16:87.
Kurtz, D. I., 1978, A decrease in the number of active mouse liver ribosomes during aging, Exp. Gerontol. 13:397.
Ladd Prosser, C., and Brown, F. A., Jr., 1961, Comparative Animal Physiology, 2nd ed., Saunders, Philadelphia.
Lansing, A. I., 1964, Age variations in cortical membranes of rotifers, J. Cell Biol. 23:403.
McKeown, F., 1965, Pathology of the Aged, Butterworths, London.
Mainwaring, W. I. P., 1969, Changes in the ribonucleic acid metabolism of the aging mouse tissues with particular reference to the prostate gland, Biochem. J. 110:79.
Miller, A., 1965, The internal anatomy of the imago of Drosophila melanogaster, in: Biology of Drosophila (M. Demerec, ed.), pp. 420–534, Hafner, New York.
Minot, C. S., 1907, The problem of age, growth and death, Popular Science Monthly 71:481.
Miquel, J., 1971, Aging of male Drosophila melanogaster: Histological, histochemical and ultrastructural observations, Adv. Gerontol. Res. 3:39.
Miquel, J., and Johnson, J. E., Jr., 1978, Senescent changes in the ribosomes of animal cells in vivo and in vitro, Mech. Ageing Dev. 8:1.
Miquel, J., Calvo, W., and Rubinstein, L. J., 1968, A simple and rapid stain for the biopsy diagnosis of brain tumors. J. Neuropathol. Exp. Neurol. 27:517.
Miquel, J., Bensch, K. G., and Philpott, D. E., 1972a, Virus-like particles in the tissues of normal and yirradiated Drosophila melanogaster, J. Invert. Pathol. 19:156
Miquel, J., Bensch, K. G., Philpott, D. E., and Atlan, H., 1972b, Natural aging and radiation-induced life shortening in Drosophila melanogaster, Mech. Ageing Dev. 1:71.
Miquel, J., Tappel, A. L., Dillard, C. J., Herman, M. M., and Bensch, K. G., 1974, Fluorescent products and lysosomal components in aging Drosophila melanogaster, J. Gerontol. 29:622.
Miquel, J., Lundgren, P. R., and Bensch, K. G., 1975, Effects of oxygen-nitrogen (1:1) at 760 Torr on the life span and fine structure of Drosophila melanogaster, Mech. Ageing Dev. 4:41.
Miquel, J., Lundgren, P. R., Bensch, K. G., and Atlan, H., 1976, Effects of temperature on the life span, vitality and fine structure of Drosophila melanogaster, Mech. Ageing Dev. 5:347.
Miquel, J., Oro, J., Bensch, K. G., and Johnson, J. E., Jr., 1977, Lipofuscin: Fine structural and biochemical studies, in: Free Radicals in Biology (W. Pryor, ed.), Vol. III, pp. 133–182, Academic Press, New York.
Miquel, J., Lundgren, P. R., and Johnson, J. E., Jr., 1978, Spectrophotometric and electron microscopic study of lipofuscin accumulation in the testis of aging mice, J. Gerontol. 33:5.
Miquel, J., Economos, A. C., Bensch, K. G., Atlan, H., and Johnson, J. E., Jr., 1979, Review of cell aging in Drosophila and mouse, Age 2:78.
Rockstein, M., and Bhatnagar, P. L., 1965, Age changes in size and number of the giant mitochondria in the flight muscle of the common housefly (Musca domestica L), J. Insect Physiol. 11:481.
Rockstein, M., and Miquel, J., 1973, Aging in insects, in: The Physiology of Insect a (M. Rockstein, ed., 2nd ed., pp. 371–478, Academic Press, New York.
Rosch, W., 1977, Der alternde Verdaungstrakt, GFR Aktuelle Gerontol. 7:115.
Sacktor, B., and Shimada, Y., 1972, Degenerative changes in the mitochondria of flight muscle from aging blow flies, J. Cell Biol. 52:465.
Seite, R., Mei, N., and Couineau, S., 1971, Modification quantitative des batonnets intranucleaires des neurones sympatiques sous l’influence de 1a stimulation electrique, Brain Res. 34:277.
Siegesmund, K. A., Dutta, C. R., and Fox, C. A., 1964, The ultrastructure of the intranuclear rodlet in certain nerve cells, J. Anat. 98:93.
Smith, D. S., 1968, Insect Cells: Their Structure and Function, Oliver & Boyd, Edinburgh.
Sohal, R. S., 1973, Fine structural alterations with age in the fat body of the adult male housefly, Musca domestica, Z. Zellforsch. Mikrosk. Anat. 140:169.
Sohal, R. S., and Allison, V. F., 1971, Age related changes in the fine structure of the flight muscle in the house fly, Exp. Gerontol. 6:167.
Sohal, R. S., and Sharma, S. P., 1972, Age related changes in the fine structure and number of neurons in the brain of the house fly Musca domestica, Exp. Gerontol. 7:243.
Strehler, B. L., 1977, Time, Cells and Ageing, Academic Press, New York.
Takahashi, A., Philpott, D. E., and Miquel, J., 1970a, Electron microscope studies on aging Drosophila melanogaster. I. Dense bodies, J. Gerontol. 25:210.
Takahashi, A., Philpott, D. E., and Miquel, J., 1970b, Electron microscope studies on aging Drosophila melanogaster. III. Flight muscle, J. Gerontol. 25:222.
Tappel, A., Fletcher, B., and Deamer, D., 1973, Effects of antioxidants and nutrients on lipid peroxidation fluorescent products and aging parameters in the mouse, J. Gerontol. 28:415.
Tate, E., 1973, The decreased density of mitochondrial cristae in heart and liver of very old mice, Gerontologist 13(2):39.
Tate, E. L., and Herbener, G. H., 1976, A morphometric study of the density of mitochondrial cristae in heart and liver of aging mice, J. Gerontol. 31:129.
Tauchi, H., and Sato, T., 1968, Age changes in size and number of mitochondria of human hepatic cells, J. Gerontol. 22:454.
Tribe, M. A., and Ashhurst, D. E., 1972, Biochemical and structural variations in the flight muscle mitochondria of aging blowflies, Calliphora erythrocephala, J. Cell Sci. 10:443.
Vann, A. C., and Webster, G. C., 1977, Age related changes in mitochondrial function in Drosophila melanogaster, Exp. Gerontol. 12:1.
Webb, S., and Tribe, M. A., 1974, Are there major degenerative changes in the flight muscle of ageing Diptera?, Exp. Gerontol. 9:43.
Wilson, P. D., and Franks, L. M., 1975, The effect of age on mitochondrial ultrastructure and enzymatic cytochemistry, Biochem. Soc. Trans. 3:126.
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© 1981 Plenum Press, New York
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Miquel, J., Economos, A.C., Bensch, K.G. (1981). Insect vs. Mammalian Aging. In: Johnson, J.E. (eds) Aging and Cell Structure. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3929-8_10
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DOI: https://doi.org/10.1007/978-1-4684-3929-8_10
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