Abstract
It is only recently that the human HLA-D locus has been recognized and analyzed. Bach and Amos (1967) and Yunis and Amos (1971) were the first to explain the “abnormal” mixed-lymphocyte reaction (MLR) between HLA-identical siblings by the existence of recombination between the classic A and B HLA loci and a “new” locus now called HLA-D.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bach, F.H., and Amos, D.B., 1967, Hu-1 major histocompatibility locus in man, Science 153:545.
Dausset, J., Legrand, L., Lepage V., Contu, L., Marcelli-Barge, A., Wildloecher, I., Benjamin, A., Meo, T., and Degos, L., 1978a, An haplo-type study of HLA complex with special reference to the HLA-DR series and to Bf-C2 and glyoxalase I polymorphism, Tissue Antigens 12(4):297.
Dausset, J., Contu, L., Legrand, L., and Rapaport, F.T., 1978b, The influence of the HLA-DR antigens on skin allografts between haploidentical individuals, Transplant. Proc. 10(4):995.
Dossetor, J.B., Kovithavongs, T., Marchk, L., Butcher, D., StLouis G., and Schlaut, J., 1975, A caucasoid isolate: Hutterites, correlation between ABCIL reactivity of a serum and stimulation by a typing cell, in: Histocompatibility Testing (F. Kissmeyer-Nielsen, ed.), pp. 620–624, Munksgaard, Copenhagen.
Eijsvoogel, V.P., Van Rood, J.J., Toit, ED., and Schellenkens, P.T.A., 1972, Position of a locus determining mixed lymphocyte reaction distinct from the known HL-A loci, Eur. J. Immunol. 2:413.
Engleman, E.G., McMichael, A.J., Batey, M.E., and McDevitt, H.O., 1978, A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen: Evidence that identity at HLA-D between suppressor and responder is required for suppression, J. Exp. Med. 147:(1):137.
Feighery, C., and Stastny, P., 1979, HLA-D region-associated determinants serve as targets for human cell-mediated lysis, J. Exp. Med. 149(2):485.
Fellous, M., Mortchelewicz, F., Kamoun, M., and Dausset, J., 1975, The use of a lymphoid cell line to define new B lymphocyte specificities, probably controlled by the MHC region, in: Histocompatibility Testing (F. Kissmeyer-Nielsen, ed.), pp. 708–712, Munksgaard, Copenhagen.
Festenstein, H., 1977, Joint report: Cellular typing, in: Histocompatibility Testing (W.F. Bodmer, J.R. Batchelor, J.G. Bodmer, H. Festentein, and P.J. Morris, eds.), pp. 358–363, Munksgaard, Copenhagen.
Fradelizi, D., Nunez-Roldan, A., and Sasportes, M., 1978, Human la-like DRw lymphocyte antigens stimulating activity in primary mixed lymphocyte reaction, Eur. J. Immunol. 8:88.
France, One and Two Regional Report, 1977, in: Histocompatibility Testing (W.F. Bodmer, J.R. Batchelor, J.G. Bodmer, H. Festinstein, and P.J. Morris, eds.), pp. 433–448, Munksgaard, Copenhagen.
Legrand, L., and Dausset, J., 1975a, Immunogenetics of a new lymphocyte system, Transplant. Proc. 7(1):5.
Legrand, L., and Dausset, J., 1975b, A second lymphocyte system (Ly-Li), in: Histocompatibility Testing (F. Kissmeyer-Nielsen, ed.), 665–670, Munksgaard, Copenhagen.
Legrand, L., and Dausset, J., 1976, The B lymphocyte Ly-Li system, Transplant. Proc. 9(1):451.
Mann, D.L., Abelson, L., Harris, S., and Amos, D.B., 1976, Second genetic locus in the HLA region for human B-cell alloantigens, Nature (London) 259(5539): 145.
McMichael, A.J., and Sasazuki, T., 1977, A suppressor T cell in the human mixed lymphocyte reaction,J. Exp. Med. 146(2):368.
Nunez-Roldan, A., Sasportes, M., and Fradelizi, D., 1978, Analysis of products involved in primary and secondary allogenic proliferation in man. II. Detection of products different from la-like, DRw antigens, activating secondary allogenic proliferation in man, Immunogenetics 6:43.
Reinsmoen, N.L., Noreen, H.J., Friend, P.S., Giblett, E.R., Greenberg, L.J., and Kersey, J.H., 1979, Anomalous mixed lymphocyte culture reactivity between HLA-A, B, C, DR identical siblings, Tissue Antigens 13(1): 1–9.
Ryder, L.P., Thomsen, M., Platz, P., and Svejgaard, H., 1975, Data reduction in LD-typing, in: Histocompatibility Testing (F. Kissmeyer-Nielsen, ed.), pp. 557–562, Munksgaard, Copenhagen.
Sasazuki, T., Kohno, Y., Iwamoto, I., Tanimira, M., Naito, S., Kashiwagi, N., Itakura, K., Aizawa, M., Hasegawa, T., Miyajima, T., Akiyama, N., Juji, T., Tsuji, K., Sekiguchi, S., Yoshida, T.O., Akaza, T., Matsuyama, M., and Toyoda, K., 1977, Japanese regional report: The relationship between HLA-D and WIA specificities in the Japanese population, in: Histocompatibility Testing (W.F. Bodmer, J.R. Batchelor, J.G. Bodmer, H. Festenstein, and P.J. Morris, eds.), pp. 489–498, Munksgaard, Copenhagen.
Sasportes, M., Fradelizi, D., Nunez-Roldan, A., Wollman, E., Giannopoulos, Z., and Dausset, J., 1978a, Analysis of stimulating products involved in primary and secondary allogenic proliferation in man. I. Preponderant role of the la-like DR (Ly-Li) antigens as stimulating products in secondary allogenic response in man, Immunogenetics 6:29.
Sasportes, M., Nunez-Roldan, A., and Fradelizi, D., 1978b, Analysis of stimulating products involved in primary and secondary allogenic proliferation in man. III. Further evidence for products different from Ia-like, DRw antigens, activating secondary allogenic proliferation in man, Immunogenetics 6:55.
Sasportes, M., Fradelizi, D., and Dausset, J., 1978c, HLA-DR specific human suppressor lymphocytes generated by repeated in vitro sensitization against allogenic cells, Nature(London) 276(5687): 502.
Sasportes, M., Wollman, E.E., Cohen, D., Fradelizi, D., Carosella, E., Cathely, G., and Dausset, J., 1979, Mise en évidence d’un facteur coluble capable d’inhiber Ia prolifération lymphocytaire allgénique chez l’Homme, C.R. Académie Sci. Paris (Ser. D) 289:41.
Solheim, B.G., Bratlie, A., Winther, N., and Thorsby, E., 1975, LD antisera prepared by planned immunizations, in: Histocompatibility Testing(F. Kissmeyer-Nielsen, ed.), pp. 713–718, Munksgaard, Copenhagen.
Suciu-Foca, N., Rohowsky, C., Godfrey, M., Khan, R., Woodward, K., Malavet, J., and Hardy, M., 1980, Intra-HLA recombinations and mapping of DR. Communication presented at the VIIIth International Workshop of Histocompatibility, Los Angeles.
Terasaki, P.I., Opeltz, G., Park, M.S., and Mickey, M.R., 1975, Four new B lymphocyte specificities, in: Histocompatibility Testing (F. Kissmeyer-Nielsen, ed.), pp. 657–664, Munksgaard, Copenhagen.
Troup, G.M., Jameson, J., Thomsen, M., Svejgaard, A., and Walford, R.L., 1978, Studies of HLA alloantigens of the Navajo Indians of North America. I. Variance of association between HLA-DRW (WIA) and HLA-DW specificities. Tissue Antigens 12(1):44.
Van Leeuwen, A., Schuit, R., and Van Rood, J.J., 1973, Typing for MLC (LD): The selection of non stimulator cells by MLC inhibition test using SD identical stimulator cells (MISIS) and fluorescent antibody studies, Transplant. Proc. 5(2): 1539.
Van Rood, J.J., Van Leeuwen, A., Keuning, J.J., and Blussévanoud Alblas, K., 1975, The serological recognition of the human MLC determinant using a modified cytotoxicity technique, Tissue Antigens 5(2):73.
Van Rood, J.J., Van Leeuwen, A., and Keuning, J.J., 1977, Evidence for two series of B-cell antigens in man and their comparison with HLA-D, Scand. J. Immunol. 6(5):373.
Walford, R.L., Smith, G.S., Zeller, E., and Wilkinson, J., 1975, A new alloantigenic system on human lymphocytes, Tissue Antigens 5(3): 196.
Walford, R.L., Ferrara, G.B., Gatti, R.A., Leibold, W., Thompson, Y.S., Mercuriali, F., Goseett, T., and Naeim, F., 1977, New groups and segregant series among B cell alloantigens of the Merrit system studies of leukemia cells, Scand. J. Immunol. 6(5):393.
Winchester, R.J., Fu, S.M., Wernet, P., Kunkel, H.G., Dupont, B., and Jershild, C., 1975, Recognition by pregnancy serums of non HLA alloantigens selectively expressed on B lymphocytes, J. Exp. Med. 141(5):924.
Yunis, E.J., and Amos, D.B., 1971, Three closely linked genetic systems relevant to transplantation, Proc. Natl. Acad. Sci. U.S.A. 68:3031.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Springer Science+Business Media New York
About this chapter
Cite this chapter
Dausset, J. (1981). Are D and DR Two Distinct Entities?. In: Reisfeld, R.A., Ferrone, S. (eds) Current Trends in Histocompatibility. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3758-4_3
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3758-4_3
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3760-7
Online ISBN: 978-1-4684-3758-4
eBook Packages: Springer Book Archive