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The Cerebral Microvasculature pp 167–178Cite as

Blood-Brain Barrier Transport During Anesthesia

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 131))

Abstract

The effects of anesthetics on the central nervous system can be described in terms of their primary direct action on membranes and enzymes or their secondary effects on brain function and metabolism. Elucidation of some of the direct effects of anesthetics on membranes such as lateral phase separation (1), membrane expansion (2,3) and membrane lipoprotein conformational changes (4) strongly suggest that alterations in membrane transport processes are likely to occur. The aim of the studies to be described was to elucidate the effects of anesthetics on blood-brain barrier (BBB) glucose transport. Changes in glucose transport may result from both the primary and secondary effects of anesthetics.

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Author information

Authors and Affiliations

  1. The Anesthesia and Critical Care Research Laboratories Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

    E. M. Nemoto

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  1. E. M. Nemoto
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Editor information

Editors and Affiliations

  1. The University of Texas, Galveston, Texas, USA

    Howard M. Eisenberg  & Robert L. Suddith  & 

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© 1980 Plenum Press, New York

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Nemoto, E.M. (1980). Blood-Brain Barrier Transport During Anesthesia. In: Eisenberg, H.M., Suddith, R.L. (eds) The Cerebral Microvasculature. Advances in Experimental Medicine and Biology, vol 131. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3752-2_14

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  • DOI: https://doi.org/10.1007/978-1-4684-3752-2_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3754-6

  • Online ISBN: 978-1-4684-3752-2

  • eBook Packages: Springer Book Archive

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