Abstract
Surface receptors have become important as markers for the characterization and classification of mononuclear cells. Most attention has been focused on the receptors for sheep erythrocytes (E receptors), complement (C receptors), and the Fc region of the immunoglobulin molecule (Fc receptors). Rosette techniques are convenient for the detection of these receptors on cells in suspension. By applying the technique of hemadsorption to tissue sections, it is also possible to use the receptors as markers in studies of the topographic distribution of mononuclear cells in normal lymphoid organs, as well as in the characterization of neoplastic and inflammatory mononuclear cell infiltrates (Shevach et al., 1973; Jaffe et al., 1975; Stingl et al., 1977; Berard et al., 1978; Bjerke et al., 1978).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Berard, C. W., Jaffe, E. S., Braylan, R. C., Mann, R. B., and Nanba, K., 1978, Immunologic aspects and pathology of the malignant lymphomas, Cancer 42: 911.
Bjerke, J. R., Krogh, H.-K., and Matre, R., 1978, Characterization of mononuclear cell infiltrates in psoriatic lesions, J. Invest. Dermatol. 71: 340.
Brubaker, D. B., and Whiteside, T. L., 1977, Localization of human T lymphocytes in tissue sections by a rosetting technique, Am. J. Pathol. 88: 323.
Christensen, B. E., Jqsnsson, V., Matre, R., and Tonder, O., 1978, Traffic of T and B lymphocytes in the normal spleen, Scand. J. Haematol. 20: 246.
Cohen, D., Gurner, B. W., and Coombs, R. R. A., 1971, A phenomenon resembling opsonic adherence shown by disaggregated cells of the transmissible venereal tumour of the dog, Br. J. Exp. Pathol. 52: 447.
Evans, R., 1976, Tumor macrophages in host immunity to malignancies, in: The Macrophage in Neoplasia ( M. Fink, ed.), pp. 27–42, Academic Press, New York.
Jaffe, E. S., Shevach, E. M., Sussman, E. H., Frank, M., Green, I., and Berard, C. W., 1975, Membrane receptor sites for the identification of lymphoreticular cells in benign and malignant conditions, Br. J. Cancer 31: 107.
Kaplan, M. E., and Clark, C., 1974, An improved rosetting assay for detection of human T lymphocytes, J. Immunol. Methods 5: 131.
Kerbel, R. S., and Pross, H. F., 1976, Fc receptor-bearing cells as a reliable marker for quantitation of host lymphoreticular infiltration of progressively growing solid tumors, Int. J. Cancer 18: 432.
Kerbel, R. S., Pross, H. F., and Elliot, E. V., 1975, Origin and partial characterization of Fc receptor-bearing cells found within experimental carcinomas and sarcomas, Int. J. Cancer 15: 918.
Lee, S.-T., and Paraskevas, F., 1978, Macrophage-T cell interactions. I. The uptake by T cells of Fc receptors released from macrophages, Cell. Immunol. 40: 141.
Matre, R., and Haugen, A., 1978, The placental Fey receptors studied using immune complexes of peroxidase, Scand. J. Immunol. 8: 187.
Matre, R., and Tonder, O., 1976, Complement receptors in human renal glomeruli, Scand. J. Immunol. 5: 917.
Matre, R., Talstad, I., and Haugen, A., 1977, Surface markers in non-phagocytic hairy cell leukemia, Acta Pathol. Microbiol. Scand. Sect. C 85: 406.
Milgrom, F., Humphrey, L. J., Tonder, O., Yasuda, J., and Witebsky, E., 1968, Antibodymediated hemadsorption by tumor tissues, Int. Arch. Allergy Appl. Immunol. 33: 478.
Roubin, R., Césarini, J.-P., Fridman, W. H., Pavie-Fischer, J., and Peter, H. H., 1975, Characterization of the mononuclear cell infiltrate in human malignant melanoma, Int. J. Cancer 16: 61.
Russell, S. W., Doe, W. F., Hoskins, R. G., and Cochrane, C. G., 1976, Inflammatory cells in solid murine neoplasms. I. Tumor disaggregation and identification of constituent inflammatory cells, Int. J. Cancer 18: 322.
Shevach, E. M., Jaffe, E. S., and Green, I., 1973, Receptors for complement and immunoglobulin on human animal lymphoid cells, Transplant. Rev. 16: 3.
Silveira, N. P. A., Mendes, N. F., and Tolnai, M. E. A., 1972, Tissue localization of two populations of human lymphocytes distinguished by membrane receptors, J. Immunol. 108: 1456.
Stingl, G., Wolff, K., Diem, E., Baumgartner, G., and Knapp, W., 1977, In situ identification of lymphoreticular cells in benign and malignant infiltrates by membrane receptor sites, J. Invest. Dermatol. 69: 231.
Tønder, O., and Krogh, H. K., 1980, Hemadsorption techniques for the in situ characterization of mononuclear cells in tissue, in: Autoimmunity in Psoriasis,(E. H. Beutner, S. Jablonska, and T. P. Chorzelski, eds.), Yearbook Medical Publishers, Chicago, in press.
Tønder, O., and Thunold, S., 1973, Receptors for immunoglobulin Fe in human malignant tissues, Scand. J. Immunol. 2: 207.
Tønder, O., Morse, P. A., Jr., and Humphrey, L. J., 1974, Similarities of Fc receptors in human malignant tissue and normal lymphoid tissue, J. Immunol. 113: 1162.
Tønder, O., Krishnan, E. C., Jewell, W. R., Morse, P. A., Jr., and Humphrey, L. J., 1976, Tumor Fc receptors and tumor-associated immunoglobulins, Acta Pathol. Microbiol. Scand. Sect. C 84: 105.
Tønder, O., Krishnan, E. C., Morse, P. A., Jr., Jewell, W. R., and Humphrey, L. J., 1978, Localization of Fc receptors in human and rat malignant tissues, Acta Pathol. Microbiol. Scand. Sect. C 86: 173.
Underwood, J. C. E., 1974, Lymphoreticular infiltration in human tumours: Prognostic and biological implications: A review, Br. J. Cancer 30: 538.
Wesenberg, F., 1978, Fcy receptors and IgG associated with human malignant tumours, Acta Pathol. Microbiol. Scand. Sect. C 86: 259.
Wesenberg, F., and Tønder, O., 1978, Evidence for nonspecifically bound IgG in human tumours, Acta Pathol. Microbiol. Scand. Sect. C 86: 251.
Witz, I. P., 1977, Tumor-bound immunoglobulins: In situ expressions of humoral immunity, Adv. Cancer Res. 25: 95.
Wood, G., and Gollahon, K. A., 1977, Detection and quantitation of macrophage infiltration into primary human tumors with the use of cell-surface markers, J. Natl. Cancer Inst. 59: 1081.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1980 Springer Science+Business Media New York
About this chapter
Cite this chapter
Tønder, O., Matre, R., Wesenberg, F. (1980). Mononuclear Cells IgG Associated with Human Malignant Tissue. In: Witz, I.P., Hanna, M.G. (eds) In Situ Expression of Tumor Immunity. Contemporary Topics in Immunobiology, vol 10. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3677-8_7
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3677-8_7
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3679-2
Online ISBN: 978-1-4684-3677-8
eBook Packages: Springer Book Archive