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O −2 and H2O2 Production During the Respiratory Burst in Alveolar Macrophages

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Macrophages and Lymphocytes

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 121B))

Abstract

It is known that the process of phagocytosis in polymorphonuclear leukocytes and in macrophages is associated with a dramatic change in oxidative metabolism. This change includes: an increase in oxygen consumption, in O −2 and H2O2 generation and in glucose catabolism through the hexose monophosphate pathway (HMP) (3,7,9,10,13,20–23,29,31,44–46,49,56). These metabolic changes are referred to as the “respiratory burst” of phagocytic cells.

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Author information

Authors and Affiliations

  1. Istituto di Patologia Generale, Trieste, Italy

    F. Rossi, G. Zabucchi, P. Dri, P. Bellavite & G. Berton

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  1. F. Rossi
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  2. G. Zabucchi
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  3. P. Dri
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  4. P. Bellavite
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  5. G. Berton
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Editor information

Editors and Affiliations

  1. Medical College of Virginia, Richmond, Virginia, USA

    Mario R. Escobar

  2. University of South Florida, Tampa, Florida, USA

    Herman Friedman

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© 1980 Plenum Press, New York

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Rossi, F., Zabucchi, G., Dri, P., Bellavite, P., Berton, G. (1980). O −2 and H2O2 Production During the Respiratory Burst in Alveolar Macrophages. In: Escobar, M.R., Friedman, H. (eds) Macrophages and Lymphocytes. Advances in Experimental Medicine and Biology, vol 121B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3593-1_5

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  • DOI: https://doi.org/10.1007/978-1-4684-3593-1_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3595-5

  • Online ISBN: 978-1-4684-3593-1

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