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Effects of UV Radiation on the Immune System: Consequences for UV Carcinogenesis

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Macrophages and Lymphocytes

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 121B))

Abstract

Since the early 1900’s, UV light has been suspected of being the causative agent for certain types of human skin cancer (1). Clinical and epidemiological data, as well as animal experiments, have provided strong evidence in support of this hypothesis (2). However, recent evidence from animal studies suggests that UV light can, in addition, affect immunologic functions, and that these immunologic perturbations may be important in the pathogenesis of UV light-induced skin cancer.

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References

  1. Dubreuilh, W. Annal. Dermat. Syph. viii (1907) 387.

    Google Scholar 

  2. Emmet, E. A. Crit. Rev. Toxicol. 2 (1973) 211.

    Article  Google Scholar 

  3. Feldmann, M. Nature New Biol. 242 (1973) 82.

    CAS  Google Scholar 

  4. Fisher, M. S. and Kripke, M. L. Proc. Natl. Acad. Sci., USA, 74 (1977) 1688.

    Article  PubMed  CAS  Google Scholar 

  5. Fisher, M. S. and Kripke, M. L. Immunol., in press.

    Google Scholar 

  6. Jessup, J. M., Cohen, M. H., Tomaschewski, M. M. and Felix, E. L. J. Natl. Cancer Inst. 57 (1976) 1077.

    PubMed  CAS  Google Scholar 

  7. Jessup, J. M., Hanna, N., Palaszynski, E. and Kripke, M. L. Cell. Immunol. 38 (1978) 105.

    Article  PubMed  CAS  Google Scholar 

  8. Kripke, M.L. J. Natl. Cancer Inst. 53 (1974) 1333.

    PubMed  CAS  Google Scholar 

  9. Kripke, M.L. Photochem. Photobiol. 24 (1976) 599.

    Article  PubMed  CAS  Google Scholar 

  10. Kripke, M.L. Photochem. Photobiol. 24 (1976) 599.

    Article  PubMed  CAS  Google Scholar 

  11. Kripke, M.L. Cancer Res. 37 (1977) 1395.

    PubMed  CAS  Google Scholar 

  12. Kripke, M.L. and Fisher, M. S. J. Reticuloendothel. Soc. 22 (1976) 599.

    Google Scholar 

  13. Kripke, M.L. Lofgreen, J. S., Beard, J., Jessup, J. M. and Fisher, M.S. J. Natl. Cancer Inst. 59 (1977) 1227.

    CAS  Google Scholar 

  14. Norbury, K.C. Kripke, M. L. and Budmen, M. B. J. Natl. Cancer Inst. 59 (1977) 1231.

    Google Scholar 

  15. Stingl, G., Katz, S. I., Shevach, E. M., Schreiner, E. and Green, I. J. J.Immunol. 120 (1978) 570.

    CAS  Google Scholar 

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© 1980 Plenum Press, New York

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Kripke, M.L. (1980). Effects of UV Radiation on the Immune System: Consequences for UV Carcinogenesis. In: Escobar, M.R., Friedman, H. (eds) Macrophages and Lymphocytes. Advances in Experimental Medicine and Biology, vol 121B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3593-1_49

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  • DOI: https://doi.org/10.1007/978-1-4684-3593-1_49

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3595-5

  • Online ISBN: 978-1-4684-3593-1

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