Res Function and Glucose Homeostasis

  • J. P. Filkins
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 121B)


As well known to members of the RE Societies, the name for the collection of wandering and sessile mononuclear phagocytic cells which we so dearly love to study was coined by the German pathologist Ludwig Aschoff as the “reticuloendothelial system”. Less well known, however, is that Aschoff in his original studies was so impressed by the metabolic functions of the phagocytic cells that he suggested an alternate term for the phagocyte collection — namely, the “histiocytic metabolic apparatus) (1). The studies to be presented herein deal with a novel, metabolic role for the macrophage apparatus — namely, a proposed regulatory function in glucose homeostasis which pivots around RES influences on insulin dynamics and the resultant functional insulinemic state.


Blood Glucose Level Glucose Homeostasis Glucose Oxidation Insulin Hypoglycemia Colloidal Carbon 
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  1. 1.
    Aschoff, L. In: Lectures in biology. Hoeber, New York (1924) 1.Google Scholar
  2. 2.
    Biozzi, G., Benacerraf, B. and Halperin, B. N. Brit. J. Exptl. Pathol. 34 (1953) 441.Google Scholar
  3. 3.
    Buchanan, B. J. and Filkins, J. P. Circ. Shock 3 (1976) 223.Google Scholar
  4. 4.
    Buchanan, B. J. and Filkins, J. P. Am. J. Physiol. 231 (1976) 265.Google Scholar
  5. 5.
    Buchanan, B. J. and Filkins, J. P.Google Scholar
  6. 6.
    Cornell, R. P. and Filkins, J. P. 145 (1974) 203.Google Scholar
  7. 7.
    Filkins, J. P. and Cornell, R. P. 265.Google Scholar
  8. 8.
    Filkins, J. P. J. Reticuloendothel. Soc. 22 (1977) 461.Google Scholar
  9. 9.
    Filkins, J. P. and Buchanan, J. B. J. Reticuloendothel. Soc. 21 (1977) 391.Google Scholar
  10. 10.
    Hadbavny, A. M., Buchanan, B. J. and Filkins, J. P. J. Reticuloendothel. Soc. 24 (1978) 57.Google Scholar

Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • J. P. Filkins
    • 1
  1. 1.Stritch School of MedicineLoyola University of ChicagoChicagoUSA

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