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Action of Porcine Follicular Fluid Oocyte Maturation Inhibitor in Vitro: Possible Role of the Cumulus Cells

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Ovarian Follicular and Corpus Luteum Function

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 112))

Abstract

Evidence has been presented in the pig that an oocyte maturation inhibitor (OMI) may be responsible for keeping the oocyte in meiotic arrest in the first prophase (1). This inhibitor is present in the fluid of antral porcine follicles. Partial purification has revealed it to be a small polypeptide with a molecular weight in the order of 2000 (2). This inhibitor prevents the spontaneous resumption of meiosis in cultured cumulus-enclosed porcine oocytes. Its inhibitory effect can be overcome by luteinizing hormone (LH) (3) and it can be reversed by removing the factor from the culture medium (4).

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References

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Authors and Affiliations

  1. Departments of Physiology and Biochemistry, University of Maryland School of Medicine, Baltimore, Maryland, 21201, USA

    T. Hillensjö, A. S. Kripner, S. H. Pomerantz & C. P. Channing

Authors
  1. T. Hillensjö
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  2. A. S. Kripner
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  3. S. H. Pomerantz
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  4. C. P. Channing
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Editor information

Editors and Affiliations

  1. Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland, USA

    Cornelia P. Channing

  2. Department of Biochemistry, University of Miami School of Medicine, Miami, Florida, USA

    John M. Marsh

  3. Center for Population Research, National Institute of Child Health and Human Development, Bethesda, Maryland, USA

    William A. Sadler

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© 1979 Plenum Press, New York

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Hillensjö, T., Kripner, A.S., Pomerantz, S.H., Channing, C.P. (1979). Action of Porcine Follicular Fluid Oocyte Maturation Inhibitor in Vitro: Possible Role of the Cumulus Cells. In: Channing, C.P., Marsh, J.M., Sadler, W.A. (eds) Ovarian Follicular and Corpus Luteum Function. Advances in Experimental Medicine and Biology, vol 112. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3474-3_33

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  • DOI: https://doi.org/10.1007/978-1-4684-3474-3_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3476-7

  • Online ISBN: 978-1-4684-3474-3

  • eBook Packages: Springer Book Archive

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