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Secretory Immunity and Infection pp 553–564Cite as

Immunoglobulin A in Secretions from the Lower Human Respiratory Tract

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 107))

Abstract

Although the focus of this Symposium is on the function of secretory immunoglobulin A (s-IgA) in the oropharynx, the domain of this fascinating, but still engimatic, immunoglobulin molecule is widespread. It is present in mucosal secretions from mucosal surfaces of the respiratory tract and the gastrointestine and it is contained in excretory fluids of the genitourinary system, lacrimal glands, breasts and the middle ear (1,2). This paper will address the role of s-IgA in the lower respiratory tract of humans through a discussion of: 1) its relative concentration in secretions obtained from the airways, 2) its molecular characteristics and 3) its function (or lack of one) in the broncho-alveolar milieu.

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Author information

Authors and Affiliations

  1. Pulmonary Section, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA

    Herbert Y. Reynolds, William M. Merrill, Edward P. Amento & Gary P. Naegel

Authors
  1. Herbert Y. Reynolds
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  2. William M. Merrill
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  3. Edward P. Amento
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  4. Gary P. Naegel
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Editor information

Editors and Affiliations

  1. Institute of Dental Research, Departments of Microbiology and Medicine, Comprehesive Cancer Center, University of Alabama in Birmingham, Birmingham, Alabama, USA

    Jerry R. McGhee , Jiri Mestecky  & James L. Babb ,  & 

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© 1978 Plenum Press, New York

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Reynolds, H.Y., Merrill, W.M., Amento, E.P., Naegel, G.P. (1978). Immunoglobulin A in Secretions from the Lower Human Respiratory Tract. In: McGhee, J.R., Mestecky, J., Babb, J.L. (eds) Secretory Immunity and Infection. Advances in Experimental Medicine and Biology, vol 107. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3369-2_63

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  • DOI: https://doi.org/10.1007/978-1-4684-3369-2_63

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3371-5

  • Online ISBN: 978-1-4684-3369-2

  • eBook Packages: Springer Book Archive

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