The Role of Antigen form and the Induction of an Intestinal Immune Response to Cholera Toxin/Toxoid in Rats
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Recent efforts to immunize against cholera have focused upon the protective role of antitoxin. We have studied the intestinal immune response to cholera toxin and toxoid in rats with two aims; first, to describe basic features of the secretory immune system of the gut using cholera toxin and toxoid as antigenic probes, and second, to provide an experimental basis for further efforts to induce antitoxic immunity in man.
KeywordsCholera Toxin Mucosal Immune Response Local Immune Response Antigen Form Booster Response
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- 4.Ruch, F. E., Murphy, J. R., Graff, L. H. and Field, M., J. Infect. Dis. in press.Google Scholar