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The Role of Antigen form and the Induction of an Intestinal Immune Response to Cholera Toxin/Toxoid in Rats

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Secretory Immunity and Infection

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 107))

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Abstract

Recent efforts to immunize against cholera have focused upon the protective role of antitoxin. We have studied the intestinal immune response to cholera toxin and toxoid in rats with two aims; first, to describe basic features of the secretory immune system of the gut using cholera toxin and toxoid as antigenic probes, and second, to provide an experimental basis for further efforts to induce antitoxic immunity in man.

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Author information

Authors and Affiliations

  1. Departments of Medicine, Baltimore City Hospitals and Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Nathaniel F. Pierce

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  1. Nathaniel F. Pierce
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Editor information

Editors and Affiliations

  1. Institute of Dental Research, Departments of Microbiology and Medicine, Comprehesive Cancer Center, University of Alabama in Birmingham, Birmingham, Alabama, USA

    Jerry R. McGhee , Jiri Mestecky  & James L. Babb ,  & 

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© 1978 Plenum Press, New York

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Pierce, N.F. (1978). The Role of Antigen form and the Induction of an Intestinal Immune Response to Cholera Toxin/Toxoid in Rats. In: McGhee, J.R., Mestecky, J., Babb, J.L. (eds) Secretory Immunity and Infection. Advances in Experimental Medicine and Biology, vol 107. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3369-2_49

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  • DOI: https://doi.org/10.1007/978-1-4684-3369-2_49

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3371-5

  • Online ISBN: 978-1-4684-3369-2

  • eBook Packages: Springer Book Archive

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