Abstract
The chyle-filled lacteals of the mesentery, and the various components of the gut-associated lymphoid tissue (GALT) were noted by the earliest anatomists, but their role in mucosal immunity became apparent relatively recently and is still a somewhat controversial topic. It is true, unfortunately, that even amongst mammals, differences in reproductive and digestive physiology and age-related changes in the GALT make a general understanding of the immune systems of their various mucosae particularly difficult. Therefore, it may be helpful to review briefly some of the factors which are thought to govern the behaviour of those lymphoid cells and humoral factors that are associated with immune reactions at mucous surfaces.
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References
Thomas, H. C. and Vaez-Zadek, F., Immunol. 26: 375, 1974.
Galbraith, R. M., Williams, R., Pattison, J., Kennedy, L. A., Eddleston, A.L.W.F., Webster, A.D.B., Doniach, D. and Batchelor, J. R., Lancet 1: 930, 1976.
Hall, J. G. and Morris, B., Quart. J. Exp. Physiol. 48: 235, 1963.
Bernstein, I. D. and Ovary, Z., Int. Arch. Allergy 33: 521, 1968.
Warshaw, A. L., Walker, W. A., Cornell, R. and Isselbacher, K. J., Lab. Invest. 25: 675, 1971.
Ogra, P. L. and Karzon, D. T., J. Immunol. 102: 1423, 1969.
Bockman, D. E. and Cooper, M. D., Am. J. Anat. 136: 455, 1973.
Reynolds, J., in The Gut-Associated Lymphoid System in Lambs, Ph.D. Thesis, Australian National University, Canberra, 1976.
Hall, J. G., Hopkins, J. and Orlans, E., Eur. J. Immunol. 7 : 30, 1977.
Scollay, R. G., Hopkins, J. and Hall, J. G., Nature, 260: 528, 1977.
Canili, R.N.P., Poskitt, D. C, Frost, H. and Trnka, Z., J. Exp. Med. 145: 420, 1977.
Hall, J. G., Hopkins, J. and Orlans, E., Biochem. Soc. Trans. 5: 1581, 1977.
Dineen, J. K. and Adams, D. B., Immunol. 19: 11, 1970.
Heath, T. J., Lascelles, A. K. and Morris, B., J. Anat. 96: 397, 1962.
Binns, R. M. and Hall, J. G., Br. J. Exp. Path. 47: 275, 1968.
Mandel, M. A. and Asofsky, R., J. Immunol. 100: 363, 1968.
Jensenius, J. C. and Williams, A. F., Eur. J. Immunol. 4: 98, 1974.
Williams, A. F. and Gowans, J. L., J. Exp. Med. 141: 335, 1975.
Hopkins, J. and Hall, J. G., Nature 259: 308, 1976.
Halstead, T. E. and Hall, J. G., Transplantation 14: 339, 1972.
Moore, A. R. and Hall, J. G., Nature 239: 161, 1972.
Pearson, L. D., Simpson-Morgan, M. W. and Morris, B., J. Exp. Med. 143: 167, 1976.
Birbeck, M.S.C., and Hall, J. G., Nature 214: 183, 1967.
Hall, J. G., Parry, D. M. and Smith, M. E., Cell Tissue Kinet. 5 : 269, 1972.
Mattioli, C. A. and Tornasi, T. B., J. Exp. Med. 138: 452, 1973.
Crabbé, P. A., Carbonara, A. O. and Heremans, J. F., Lab. Invest. 14 : 235, 1965.
Lascelles, A. K. and McDowell, G. H., Transplant. Rev. 19: 170, 1974.
Lamm, M. E., Adv. Immunol. 22: 223, 1976.
Vaerman, J. P., André, C., Bazin, H. and Heremans, J. F., Eur. J. Immunol. 3: 580, 1973.
Bazin, H., Beckers, A. and Querinjean, P., Eur. J. Immunol. 4: 44, 1974.
Kaartinen, M., Hume, M. and Makela, O., Nature 252: 239, 1974.
Lemaitre-Coelho, I., Jackson, G.D.F. and Vaerman, J. P., Eur. J. Immunol. 8: 588, 1977.
Orlans, E., Peppard, J., Reynolds, J. and Hall, J. G., J. Exp. Med., in press.
Ashwell, G. and Morell, A. G., Adv. Enzymol. 41: 99, 1974.
Thomas, P., Birbeck, M.S.C., and Cartwright, P., Biochem. Soc. Trans. 5: 312, 1977.
Heremans, J. F., in The Antigens (Edited by Sela, M.), Vol. II, Academic Press, New York, 1974.
Bjørnboe, M., Prytz, H. and Ørskov, F., Lancet, 1: 58, 1972.
Porter, P., Noakes, D. E. and Allen, W. D., Immunol. 18: 909, 1970.
Smith, W. D., Dawson, A. M., Wells, P. W. and Burrells, C., Res. Vet. Sci. 19: 189, 1975.
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Hall, J., Orlans, E., Peppard, J., Reynolds, J. (1978). Lymphatic Physiology and Secretory Immunity. In: McGhee, J.R., Mestecky, J., Babb, J.L. (eds) Secretory Immunity and Infection. Advances in Experimental Medicine and Biology, vol 107. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3369-2_4
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DOI: https://doi.org/10.1007/978-1-4684-3369-2_4
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