Studies of Secretory IgA in Caries-Resistant and Caries-Susceptible Adults

  • Robert N. Stuchell
  • Irwin D. Mandel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)


The relationship of secretory IgA (s-IgA) to dental caries has intrigued a large number of investigators. Among the early observations, Lehner et al. (1) reported higher IgA levels in the whole saliva of caries-free subjects than in caries-active subjects; Zengo et al. (2) reported significantly higher levels of IgA in submaxillary saliva of the caries resistant subjects when compared to caries susceptible subjects. Shklair et al. (3) on the other hand, found no differences in the levels of IgA in parotid and whole saliva when caries-free and caries-active Naval recruits were compared.


Dental Caries Resistant Group Parotid Saliva Caries Activity Unstimulated Saliva 
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    Lehner, T., Caldwell, J. F. and Clarry, E. D., Lancet 1: 1294, 1967.PubMedCrossRefGoogle Scholar
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    Zengo, A. N., Mandel, I. D., Goldman, R. and Khurana, H. S., Arch. Oral Biol. 16: 557, 1971.PubMedCrossRefGoogle Scholar
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Robert N. Stuchell
    • 1
  • Irwin D. Mandel
    • 1
  1. 1.Division of Preventive Dentistry, School of Dental and Oral SurgeryColumbia UniversityNew YorkUSA

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