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I would like to ask a question of Dr. Lally. You tried to see various kinds of T-cell effects on the IgA response engendered by splenic cells. I was wondering if you have tried the effect of carrier-primed suppressor cells made in the Tada manner. We found that transfer of Peyer’s patch cells resulted in an IgA response and it was T-cell dependent. When we looked at the effect of T cells that were generated to be suppressive, we found that of all the responsives, the IgA response was least affected. However, spleen IgA precursors seem more primary than those from Peyer’s patches. One might predict then, that kinds of splenic cells that are generating these IgA responses, might be more likely to be suppressed. Have you looked at this?
KeywordsSplenic Cell Lipoid Pneumonia Selection Phenomenon Secretory Immunity Main Fermentor
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