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The Reticuloendothelial System in Health and Disease pp 155–178Cite as

Primary Immunodeficiency Diseases

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 73B))

Abstract

Rare individuals, experiments of nature who suffer the often devastating consequences of a congenital defect within the immune system, have served to teach us much of what we know today about the complex immune response of man (36,39,54). From a careful study of them and their diseases, together with related studies in the laboratory, we have learned, for example, that there are two major and quite separate arms making up the immune system of man and animals. These two basic components are now known as (1) cell-mediated immunity (CMI), or the T-cell (T for thymus derived) system, and (2) humoral immunity, or the B-cell (bone marrow or bursa-derived) system.

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Authors and Affiliations

  1. Memorial Sloan-Kettering Cancer Center, New York, New York, 10021, USA

    R. A. Good & M. A. Hansen

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  1. Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA

    Herman Friedman

  2. Medical College of Virginia, Richmond, Virginia, USA

    Mario R. Escobar

  3. Medical College of Georgia, Augusta, Georgia, USA

    Sherwood M. Reichard

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Good, R.A., Hansen, M.A. (1976). Primary Immunodeficiency Diseases. In: Friedman, H., Escobar, M.R., Reichard, S.M. (eds) The Reticuloendothelial System in Health and Disease. Advances in Experimental Medicine and Biology, vol 73B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3300-5_14

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