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Cellular Basis for the Generation of B-Cell Diversity

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The Reticuloendothelial System in Health and Disease

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 73))

Abstract

Birds, especially domestic strains of chicken, have provided pivotal models for the study of certain aspects of the organization of the immune system in higher vertebrates. Many of the principles of the graft-versus-host phenomenon and the surprisingly high frequency of lymphocytes reactive to histocompatibility antigens were elucidated originally in chickens (41). At about the same time, the avian bursa of Fabricius was found to control development of antibody responsiveness (13). Later the bursa was shown to be essential for the development of avian lymphoid leukosis (35). These findings, and the discoveries in mammals of the central roles played by the thymus in lymphomagenesis and in normal development of immunocompetent cells, paved the way for elucidation of the separate pathways followed by thymus (T) and bursal or bursa-equivalent (B) lines of lymphoid cells during normal and neoplastic development (8,9,47). Studies in the chick also provided a firm embryologic basis for the concept of a mesenchymal origin of hemopoietic stem cells for both T and B and other blood cell lines (31).

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References

  1. Albini, B. and Wick, G., Nature, 249 (1974) 653.

    Article  PubMed  CAS  Google Scholar 

  2. Albini, B. and Wick, G., Int. Arch. Allergy, 48 (1975) 513.

    Article  PubMed  CAS  Google Scholar 

  3. Albini, B., Wick, G., Orlans, E. and Rose, M.E., Int. Arch. Allergy, 47 (1974) 23.

    Article  PubMed  CAS  Google Scholar 

  4. Bankhurst, A.D., Rouse, B.T. and Warner, N.L., Int. Arch. Allergy, 42 (1972) 187.

    Article  PubMed  CAS  Google Scholar 

  5. Bockman, D.E. and Cooper, M.D., Am. J. Anatomy, 136 (1973) 455.

    Article  CAS  Google Scholar 

  6. Cairns, J., Nature, 255 (1975) 197.

    Article  PubMed  CAS  Google Scholar 

  7. Cooper, M.D., Cain, W.A., Van Alten, P.J. and Good, R.A., Int. Arch. Allergy, 35 (1969) 242.

    Article  PubMed  CAS  Google Scholar 

  8. Cooper, M.D., Peterson, R.D.A., Gabrielsen, A.E. and Good, R.A., Cancer Res., 26 (1966) 1165.

    PubMed  CAS  Google Scholar 

  9. Cooper, M.D., Peterson, R.D.A., South, M.A. and Good, R.A., J. Exp. Med., 123 (1966) 75.

    Article  PubMed  CAS  Google Scholar 

  10. Droege, W., Proc. Nat. Acad. Sci., 72 (1975) 2371.

    Google Scholar 

  11. Dwyer, J.M. and Warner, N.L., Nature, 229 (1971) 210.

    CAS  Google Scholar 

  12. Gaily, J.A. and Edelman. G.M., Nature. 227 (1970) 341.

    Article  Google Scholar 

  13. Glick, B., Chang, T.S. and Jaap, R.G., Poultry Sci., 35 (1956) 224.

    Article  Google Scholar 

  14. Hudson, L. and Roitt, I.M., Europ. J. Immunol. 3 (1973) 63.

    Article  CAS  Google Scholar 

  15. Ivanyi, J., Immunology 28 (1975) 1007.

    PubMed  CAS  Google Scholar 

  16. Ivanyi, J., Murgatroyd, L.B. and Lydyard, P.M., Immunology, 23 (1972) 107.

    PubMed  CAS  Google Scholar 

  17. Ivanyi, J. and Salerno, A., Immunology, 22 (1972) 247.

    PubMed  CAS  Google Scholar 

  18. Jerne, N.K., Europ. J. Immunol., 1 (1971) 1.

    Article  CAS  Google Scholar 

  19. Kincade, P.W. and Cooper, M.D., J. Immunol., 106 (1971) 371.

    PubMed  CAS  Google Scholar 

  20. Kincade, P.W. and Cooper, M.D., Science, 179 (1973) 398.

    Article  PubMed  CAS  Google Scholar 

  21. Kincade, P.W., Lawton, A.R., Bockman, D.E. and Cooper, M.D., Proc. Nat. Acad. Sci., 67 (1970) 1918.

    Article  PubMed  CAS  Google Scholar 

  22. Kincade, P.W., Lawton, A.R. and Cooper, M.D., J. Immunol., 106 (1971) 1421.

    PubMed  CAS  Google Scholar 

  23. Kincade, P.W., Self, K.S. and Cooper, M.D., Cell. Immunol., 8 (1973) 93.

    Article  PubMed  CAS  Google Scholar 

  24. Kirchner, H., Oppenheim, J.J., Blaese, M.R. and Hofstrand, H.J., J. Immunol., 109 (1972) 348.

    PubMed  CAS  Google Scholar 

  25. Lawton, A.R., Kincade, P.W. and Cooper, M.D., Fed. Proc. 34 (1975) 33.

    PubMed  CAS  Google Scholar 

  26. Lebacq-Verheyden, A-M., Vaerman, J.P. and Heremans, J.F., J. Immunol., 109 (1972) 652.

    PubMed  CAS  Google Scholar 

  27. Le Douarin, N.M., Houssaint, E., Jotereau, F.V. and Belo, M., Proc. Natl. Acad. Sci., 72 (1975) 2701.

    Google Scholar 

  28. Le Douarin, N.M. and Jotereau, F.V., J. Exp. Med., 142 (1975) 17

    Article  PubMed  Google Scholar 

  29. Leslie, G.A. and Martin, L.N., J. Immunol., 110 (1973) 959.

    CAS  Google Scholar 

  30. McBride, R.A. and Schierman, W., J. Immunol., 110 (1973) 1710.

    Google Scholar 

  31. Moore, M.A.S. and Owen, J.J.T., Lancet, ii (1967) 658.

    Google Scholar 

  32. Osmond, D.G. and Nossal, G.J.V., Cell. Immunol., 13 (1974) 132.

    Article  PubMed  CAS  Google Scholar 

  33. Perey, D.Y.E. and Bienenstock, J., J. Immunol., 111 (1973) 633.

    PubMed  CAS  Google Scholar 

  34. Peterson, R.D., Alm, G.V. and Michalek, S., J. Immunol., 106 (1971) 1609.

    Google Scholar 

  35. Peterson, R.D.A., Purchase, H.G., Burmester, B.R., Cooper, M.D. and Good, R.A., J. Natl. Cancer Inst., 36 (1966) 585.

    PubMed  CAS  Google Scholar 

  36. Potworowski, E.F., Immunology, 23 (1972) 199.

    PubMed  CAS  Google Scholar 

  37. Rabellino, E. and Grey, H.M., J. Immunol., 106 (1971) 1418.

    Google Scholar 

  38. Rubin, E., Cooper, M.D. and Kraus, F.W., Bacteriol. Proc., 71 (1971) 67.

    Google Scholar 

  39. Ryser, J-E. and Vassalli, P., J. Immunol., 113 (1974) 719.

    PubMed  CAS  Google Scholar 

  40. Shaffner, T., Mueller, J., Hess, M.W., Cottier, H., Sordat, B. and Ropke, C., Cell. Immunol., 13 (1974) 304.

    Article  Google Scholar 

  41. Simonsen, M., Prog. Allergy, 6 (1962) 349.

    PubMed  CAS  Google Scholar 

  42. Sorvari, T., Sorvari, R., Ruotsalainen, P., Toivanen, A. and Toivanen, P., Nature, 253 (1975) 217.

    Article  PubMed  CAS  Google Scholar 

  43. Tao-Wiedmann, T-W., Loor, F. and Hagg, L-B., Immunology, 28 (1975) 821.

    PubMed  CAS  Google Scholar 

  44. Thorbecke, G.J., Warner, N.L., Hochwald, G.M. and Ghanian, S.H., Immunology, 15 (1968) 123.

    PubMed  CAS  Google Scholar 

  45. Tufveson, G. and Alm, G.V., Int. Arch. Allergy, 48 (1975) 537.

    Article  PubMed  CAS  Google Scholar 

  46. Warner, N.L., Aust. J. Exp. Biol. Med. Sci., 42 (1964) 401.

    Article  PubMed  CAS  Google Scholar 

  47. Warner, N.L., Szenberg, A. and Burnet, F.M., Australian J. Exp. Biol. and Med. Sci., 40 (1962) 373.

    Article  CAS  Google Scholar 

  48. Webb, S.R. and Cooper, M.D., J. Immunol., 111 (1973) 275.

    PubMed  CAS  Google Scholar 

  49. Weinbaum, F.I., Gilmour, D.G. and Thorbecke, G.J., J. Immunol., 110 (1973) 1434.

    Google Scholar 

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Author information

Authors and Affiliations

  1. University of Alabama, Birmingham, Alabama, USA

    M. D. Cooper & P. M. Lydyard

  2. Department of Anatomy, University of Genova, Italy

    C. E. Grossi

Authors
  1. M. D. Cooper
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  2. C. E. Grossi
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  3. P. M. Lydyard
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Editor information

Editors and Affiliations

  1. Medical College of Georgia, Augusta, Georgia, USA

    Sherwood M. Reichard

  2. Medical College of Virginia, Richmond, Virginia, USA

    Mario R. Escobar

  3. Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA

    Herman Friedman

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© 1976 Plenum Press, New York

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Cooper, M.D., Grossi, C.E., Lydyard, P.M. (1976). Cellular Basis for the Generation of B-Cell Diversity. In: Reichard, S.M., Escobar, M.R., Friedman, H. (eds) The Reticuloendothelial System in Health and Disease. Advances in Experimental Medicine and Biology, vol 73. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3297-8_4

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  • DOI: https://doi.org/10.1007/978-1-4684-3297-8_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3299-2

  • Online ISBN: 978-1-4684-3297-8

  • eBook Packages: Springer Book Archive

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