Abstract
In 1948 Beeson (3) reported that granulocytes contain an endogenous pyrogen, which was later (4,5) shown to differ from the pyrogenic endotoxin of gram negative bacteria. Considerable work on the pathogenesis of fever by several investigators eventually yielded an experimental model for it (Fig. 1).
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© 1976 Plenum Press, New York
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Mitchell, R.H., Gander, G.W., Goodale, F. (1976). The Role of Phagocytosis in the Production of Endogenous Pyrogen by Polymorphonuclear Leukocytes. In: Reichard, S.M., Escobar, M.R., Friedman, H. (eds) The Reticuloendothelial System in Health and Disease. Advances in Experimental Medicine and Biology, vol 73. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3297-8_22
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DOI: https://doi.org/10.1007/978-1-4684-3297-8_22
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