Skip to main content

Incorporation of Purine Bases by Intact Red Blood Cells

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 76B))

Abstract

Mature human erythrocytes do not possess the ability to perform purine synthesis de novo (1–3). These cells meet their requirements for purine nucleotides by re-utilisation of preformed bases that are derived from the diet and those released from other tissues into the blood circulation (1,4).

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Lowy B.A., Ramot B. and London I.M. (1960). J.Biol.Chem. 235, 2920–2924.

    PubMed  CAS  Google Scholar 

  2. Lowy B.A., Williams M.K. and London I.M. (1962). J.Biol.Chem. 237, 1622–1626.

    PubMed  CAS  Google Scholar 

  3. Fontenelle L.J. and Henderson J.F. (1969). Biochim. Biophys.Acta 177, 175–177.

    Article  PubMed  CAS  Google Scholar 

  4. Henderson J.F. and Le Page G.A. (1959). J.Biol.Chem. 234, 3219–3224.

    PubMed  CAS  Google Scholar 

  5. Whittam R. (1960). J.Physiol.London 154, 614–623.

    PubMed  CAS  Google Scholar 

  6. Lassen U.V. (1967).Biochim.Biophys.Acta 135, 146–154.

    Article  PubMed  CAS  Google Scholar 

  7. Sixma J.J., Holmsen H. and Trieschnigg A.C.M. (1973), Biochim. Biophys. Acta 298, 460–468.

    Article  PubMed  CAS  Google Scholar 

  8. Hochstadt-Ozer J. and Stadtman E.R. (1971). J.Biol.Chem. 246, 5304–5320.

    PubMed  CAS  Google Scholar 

  9. de Bruyn C.H.M.M. and Oei T.L. (1974). In: Purine Metabolism in Man (Sperling O., de Vries A. and Wijngaarden J.B. Eds.) pp.223–227. Plenum Press, New York.

    Google Scholar 

  10. Seegmiller J.E., Rosenbloom F.M. and Kelley W.N. (1967). Science 155, 1682–1684.

    Article  PubMed  CAS  Google Scholar 

  11. Greene M.L., Boyle J.A. and Seegmiller J.E. (1970). Science 167, 887–889.

    Article  PubMed  CAS  Google Scholar 

  12. Hershko A., Razin A., Shoshani T. and Mager J. (1967). Biochim.Biophys. Acta 149, 59–7 3.

    PubMed  CAS  Google Scholar 

  13. de Bruyn C.H.M.M. and Oei T.L. (1976). These Proceedings.

    Google Scholar 

  14. Henderson J.F. and Le Page (1959). Cancer Res. 19, 67–71.

    PubMed  CAS  Google Scholar 

  15. Hawkins R.A. and Berlin R.D. (1969). Biochim. Biophys. Acta 173, 324–337.

    Article  PubMed  CAS  Google Scholar 

  16. Kundig W., Kundig F., Anderson B. and Roseman S. (1966). J.Biol.Chem. 241, 3243–3246.

    PubMed  CAS  Google Scholar 

  17. Kaback H.R. (1968). J.Biol.Chem. 243, 3711–3724.

    PubMed  CAS  Google Scholar 

  18. Berlin R.D. and Stadtman R.D. (1966). J.Biol.Chem 241, 2679–2686.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1977 Plenum Press, New York

About this chapter

Cite this chapter

de Bruyn, C.H.M.M., Oei, T.L. (1977). Incorporation of Purine Bases by Intact Red Blood Cells. In: Müller, M.M., Kaiser, E., Seegmiller, J.E. (eds) Purine Metabolism in Man—II. Advances in Experimental Medicine and Biology, vol 76B. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3285-5_20

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-3285-5_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3287-9

  • Online ISBN: 978-1-4684-3285-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics