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The Role of Membrane Damage in Radiation-Induced Cell Death

  • Chapter
Membrane Toxicity

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 84))

Abstract

Radiation-induced cell death is probably mediated primarily through deposition of energy, in single events, in a few vital macromolecules, or targets, the integrity of which is indispensable for proliferation. The genome is customarily regarded as the main target, but several lines of evidence support the inference that there are important consequences of events in nuclear membranes in eukaryotes, and plasma membrane in bacteria.

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Authors and Affiliations

  1. Gray Laboratory of the Cancer Research Campaign, Mount Vernon Hospital, Northwood, HA6 2RN, UK

    Tikvah Alper D.Sc.

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  1. Tikvah Alper D.Sc.
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Editors and Affiliations

  1. The University of Rochester, Rochester, New York, USA

    Morton W. Miller  & Adil E. Shamoo  & 

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© 1977 Plenum Press, New York

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Alper, T. (1977). The Role of Membrane Damage in Radiation-Induced Cell Death. In: Miller, M.W., Shamoo, A.E. (eds) Membrane Toxicity. Advances in Experimental Medicine and Biology, vol 84. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3279-4_7

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  • DOI: https://doi.org/10.1007/978-1-4684-3279-4_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3281-7

  • Online ISBN: 978-1-4684-3279-4

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