Abstract
The transport of metabolites to and from the central nervous system is of considerable interest. To a greater extent than most other tissues, central nervous system tissue in vitro takes up amino acids to well above their concentrations in the incubation medium. Presumably the transport systems responsible for this uptake and for efflux in vitro are also those responsible for transport between brain cells in living animals2.
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References
Bonavita, V., Developmental changes of enzyme patterns in the nervous tissue. In: H. Peeters (ed) Protides of the Biological Fluids, Elsevier Publ. Co., Amsterdam, (1966) p. 163.
Cohen, R.S., and Lajtha, A., Amino acid transport. In: A. Lajtha (ed.) Handbook of Neurochemistry, Plenum Press, N.Y. (1972) p. 545–574.
Fazekas, J.F., Alexander, F.A.D., and Himwich, H.E., Tolerance of the newborn to anoxia, Amer. J. Physiol., 134 (1941) 281.
Ferguson, R.K., and Woodbury, D.M., Penetration of 14C-inulin and 14C-sucrose into brain, cerebrospinal fluid, and skeletal muscle of developing rats, Exp. Brain Res., 7 (1969) 181.
Jilek, L., Fischer, J., Krulick, L., and Trojan, S., The reaction of the brain to stagnant hypoxia and anoxia during ontogeny. In: W.A. Himwich and H.E. Himwich (Eds.) The Developing Brain, Elsevier, Amsterdam, (1964) p. 113.
Lahiri, S., and Lajtha, A., Cerebral amino acid transport in vitro. I. Some requirements and properties of uptake, J. Neurochem., 11 (1964) 77.
Lajtha, A., and Piccoli, F., Alterations related to the cerebral free amino acid pool during development. In: D.C. Pease (ed.) Cellular Aspects of Neuronal Growth and Differentiation, U.C.L.A. Forum Med. Sci. Vol. 14 (1971) p. 419.
Levi, G., Development of amino acid transport systems in incubated tissue. In: W.A. Himwich (ed.) Biochemistry of the Developing Brain, Dekker, N.Y. (1973) p. 187–218.
Lowry, O.H., Roberts, N.R., and Lewis, C., The quantitative histochemistry of the retina, J. Biol. Chem., 220 (1956) 879.
Piccoli, F., Grynbaum, A., and Lajtha, A., Developmental changes in Na+, K+ and ATP and in the levels and transport of amino acids in incubated slices of rat brain, J. Neurochem. 18 (1971) 1135.
Piccoli, F., Guarneri, R., Savettieri, G., and Bonavita, V., ATP e ATPasi nell′encefalo di ratto durante lo sviluppo. Acta neurol., 27 (1972) 501.
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© 1976 Plenum Press, New York
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Piccoli, F. (1976). Changes in Cerebral Amino Acid Transport During Development. In: Levi, G., Battistin, L., Lajtha, A. (eds) Transport Phenomena in the Nervous System. Advances in Experimental Medicine and Biology, vol 69. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-3264-0_30
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DOI: https://doi.org/10.1007/978-1-4684-3264-0_30
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