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Mechanisms of Transport for the Uptake and Release of Biogenic Amines in Nerve Endings

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Transport Phenomena in the Nervous System

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 69))

Abstract

Reports on the amine transport mechanism located at the plasma membrane of nerve endings have been extensively reviewed for general characteristics 30, 31, 49, and for the effects of electrolytes 46. The nerve ending is uncommon, or unique in the sense that the product of secretion is recaptured almost immediately by the secretory organ. Transport, therefore, may be a bidirectional phenomenon in nerve endings. As a result of investigations, a synaptic sub-unit is envisaged in which electrolytes play an important role in the mobilization of amine as well as for transport in both directions.

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Author information

Authors and Affiliations

  1. Section on Biochemical Pharmacology, Hypertension-Endocrine Branch, National Heart and Lung Institute, National Institutes of Health, 20014, Bethesda, Maryland, USA

    Donald F. Bogdanski

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  1. Donald F. Bogdanski
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Editors and Affiliations

  1. National Research Council, Rome, Italy

    Giulio Levi

  2. University of Padua Medical School, Padua, Italy

    Leontino Battistin

  3. Research Institute of Neurochemistry, New York, New York, USA

    Abel Lajtha

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© 1976 Plenum Press, New York

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Bogdanski, D.F. (1976). Mechanisms of Transport for the Uptake and Release of Biogenic Amines in Nerve Endings. In: Levi, G., Battistin, L., Lajtha, A. (eds) Transport Phenomena in the Nervous System. Advances in Experimental Medicine and Biology, vol 69. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-3264-0_22

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  • DOI: https://doi.org/10.1007/978-1-4684-3264-0_22

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