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The Effects of Tolbutamide on the Development of Atherosclerosis in Rhesus Monkeys Fed an Average American Table-Prepared Diet

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Lipids, Lipoproteins, and Drugs

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 63))

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Abstract

Fourteen adult male Rhesus monkeys were followed for 18 months during which they all consumed daily measured portions of a simulated average American diet whose ingredients were based on average food consumption figures for the USA. Seven of these animals, each paired with a comparable control, were also fed 20 mg/kg of Tolbutamide per day. No significant differences in weight gain, glucose tolerance, electrocardiograms or serum lipids were noted on numerous determinations during this period of study.

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© 1975 Plenum Press, New York

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Wissler, R.W., Borensztajn, J., Rubenstein, A., Getz, G., Vesselinovitch, D. (1975). The Effects of Tolbutamide on the Development of Atherosclerosis in Rhesus Monkeys Fed an Average American Table-Prepared Diet. In: Kritchevsky, D., Paoletti, R., Holmes, W.L. (eds) Lipids, Lipoproteins, and Drugs. Advances in Experimental Medicine and Biology, vol 63. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3258-9_28

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  • DOI: https://doi.org/10.1007/978-1-4684-3258-9_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3260-2

  • Online ISBN: 978-1-4684-3258-9

  • eBook Packages: Springer Book Archive

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