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The Origin of Pandemic Strains of Influenza. Evidence from Studies of the Structure of the Hemagglutinin Subunits

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Immunity in Viral and Rickettsial Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 31))

Abstract

Influenza continues to be one of the major epidemic diseases of man. Pandemics of influenza A occur at irregular intervals, with intervening outbreaks of reduced severity. Between pandemics the virus slowly changes, undergoing gradual alterations in its surface antigens (immunological, or antigenic drift); but the major epidemics are caused by new virus strains having surface antigens unrelated to those of viruses currently circulating.

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Author information

Authors and Affiliations

  1. Department of Microbiology, The John Curtin School of Medical Research, Australian National University, Canberra, Australia

    W. G. Laver

Authors
  1. W. G. Laver
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Editor information

Editors and Affiliations

  1. Israel Institute for Biological Research, Ness-Ziona, Israel

    Alexander Kohn (Director) (Director)

  2. Tel-Aviv University Medical School, Israel

    Alexander Kohn (Director) & Marcus A. Klingberg (Head) (Director) &  (Head)

  3. Department of Epidemiology, Israel Institute for Biological Research, Ness-Ziona, Israel

    Marcus A. Klingberg (Head) (Head)

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© 1972 Plenum Press, New York

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Laver, W.G. (1972). The Origin of Pandemic Strains of Influenza. Evidence from Studies of the Structure of the Hemagglutinin Subunits. In: Kohn, A., Klingberg, M.A. (eds) Immunity in Viral and Rickettsial Diseases. Advances in Experimental Medicine and Biology, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3225-1_4

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  • DOI: https://doi.org/10.1007/978-1-4684-3225-1_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3227-5

  • Online ISBN: 978-1-4684-3225-1

  • eBook Packages: Springer Book Archive

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