Red Cell Hexosemonophosphate Shunt Deficiency in Uremia

  • Harry Jacob
  • Yoshihito Yawata
  • Robert Howe
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


Shortened red cell survival commonly occurs in uremia. Although the present studies indicate that hemolysis is by no means universal in patients with renal failure, hemolytic anemia can, in fact, be troublesome, especially in hemodialysis units (Huntley et al., 1971). The pathogenesis of uremic hemolysis is uncertain, but it is clear that it occurs unpredictably with a severity unrelated to the degree of renal failure (Erslev, 1970; Eklund et al., 1971).


Methylene Blue G6PD Deficiency Sodium Ascorbate Uremic Patient Metabolic Defect 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Harry Jacob
  • Yoshihito Yawata
  • Robert Howe
    • 1
  1. 1.Department of Medicine and Section of HematologyUniversity of Minnesota Medical SchoolMinneapolisUSA

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