Red Cell Hexosemonophosphate Shunt Deficiency in Uremia
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Shortened red cell survival commonly occurs in uremia. Although the present studies indicate that hemolysis is by no means universal in patients with renal failure, hemolytic anemia can, in fact, be troublesome, especially in hemodialysis units (Huntley et al., 1971). The pathogenesis of uremic hemolysis is uncertain, but it is clear that it occurs unpredictably with a severity unrelated to the degree of renal failure (Erslev, 1970; Eklund et al., 1971).
KeywordsMethylene Blue G6PD Deficiency Sodium Ascorbate Uremic Patient Metabolic Defect
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