Rejuvenation and Freezing of Outdated Human Red Cells

  • C. Robert Valeri
  • Charles G. Zaroulis
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


The 24-hour posttransfusion survival value, the mechanism of removal of the nonviable compatible red cells, the spontaneous hemolysis that occurs in vitro with storage, and the potential toxicity of additives used in the preservation procedure have all served as criteria for satisfactory preservation of human red cells (Valeri, 1970a and 1971). Of current concern is the ability of preserved red cells to maintain normal oxygen transport function at the time of transfusion.


Uric Acid Level Disodium Phosphate Mmoles Glucose Oxyhemoglobin Dissociation Curve Oxygen Transport Function 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • C. Robert Valeri
    • 1
  • Charles G. Zaroulis
    • 1
  1. 1.Naval Blood Research LaboratoryChelseaUSA

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