The Contribution of Carbamate in Human Adult and Foetal Blood to the CO2 Exchange During the Respiratory Cycle

  • Christian Bauer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


The reaction of carbon dioxide with the unprotonated form of amino groups yields carbamate and hydrogen ions according to the following reaction scheme:
$$R\, - \,NH_3^ + \, + \,\overset {K_z^1} \leftrightarrows \,R\, - \,N{H_2}\, + \,{H^ + }$$
$$ R\, - \,N{H_2}\, + \,C{O_2}\overset {K_c^1} \leftrightarrows \,R\, - \,NHCO{O^{ - \,}}\, + \,{H^ + }$$
At the hemoglobin molecule this reaction proceeds at the N-terminal amino groups of both α and β chins as it has been demonstrated by Kilmartin & Rossi-Bernardi (1969, 1971).


Foetal Blood Oxygen Affinity Organic Phosphate Human Hemoglobin Bohr Effect 
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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • Christian Bauer
    • 1
  1. 1.Physiologisches Institut der Medizinischen Hochschule3 HannoverW. Germany

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