The Role of Carbonic Anhydrase in the Control of Intracellular pH

  • William J. Waddell
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 28)


In spite of the obvious importance of carbonic anhydrase in affecting the pH value of biological fluids, there are surprisingly few studies on its contribution to the regulation of intracellular pH. There are two studies on the effect of inhibition of carbonic anhydrase on the intracellular pH of rat brain.


Carbonic Anhydrase Exit Channel Organic Phosphate Shell Gland Electrochemical Equilibrium 
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  1. Duhm, J. (1971). Pflugers Arch. 326: 341.PubMedCrossRefGoogle Scholar
  2. Fitzsimmons, E. J. and Sendroy, J. Jr. (1961). J. Biol. Chem. 236: 1595.Google Scholar
  3. Funder, J. and Wieth, J. O. (1966). Acta Physiol. Scand. 68: 234.CrossRefGoogle Scholar
  4. Hammarstrom, L., Appelgren, L.-E. and Ullberg, S. (1965). Exp. Cell Res. 37: 608.CrossRefGoogle Scholar
  5. Kjällquist, Å. and Siesjö, B. K. (1966). Acta Physiol. Scand. 68: 255.CrossRefGoogle Scholar
  6. Koch, A. and Woodbury, D. M. (1960). Amer. J. Physiol. 198: 434.PubMedGoogle Scholar
  7. Maren, T. H. (1972). Amer. J. Physiol. In press.Google Scholar
  8. Maren, T. H. and Broder, L. E. (1970). J. Pharmacol. Exptl. Therap. 172: 197.Google Scholar
  9. Poole, D. T. (1967). J. Biol. Chem. 242: 3731.PubMedGoogle Scholar
  10. Poole, D. T., Butler, T. C. and Waddell, W. J. (1964). J. Nat. Cancer Inst. 32: 939.Google Scholar
  11. Simkiss, K. (1970). J. Physiol. 207: 63 P.Google Scholar
  12. Waddell, W. J. (1972). Chest 61: 56S.PubMedCrossRefGoogle Scholar
  13. Waddell, W. J. and Bates, R. G. (1969). Physiol. Rev. 49: 285.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • William J. Waddell
    • 1
    • 2
  1. 1.Dental Research CenterUniversity of North CarolinaChapel HillUSA
  2. 2.Department of PharmacologyUniversity of Kentucky College of MedicineLexingtonUSA

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