Abstract
There are five different abnormal haemoglobins which cause methaemoglobinaemia. In four of these the action of methaemoglobin reductase is ineffective because either the proximal or the distal haem-linked histidines in one pair of subunits have been replaced by tyrosines, and in the fifth, known as haemoglobin M Milwaukee (Hb Mil), because valines Ell(67) β have been replaced by glutamic acids (Gerald and Efron, 1961).
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© 1972 Plenum Press, New York
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Perutz, M.F., Pulsinelli, P.D., Ranney, H.M. (1972). Structure of Haemoglobin M Milwaukee, A Mutant Form Exhibiting Interaction Between Ferrous and Ferric Subunits. In: Brewer, G.J. (eds) Hemoglobin and Red Cell Structure and Function. Advances in Experimental Medicine and Biology, vol 28. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3222-0_1
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DOI: https://doi.org/10.1007/978-1-4684-3222-0_1
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