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Comparative Cardiovascular Adaptation to Exercise in Animals and Man and its Relevance to Coronary Heart Disease

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Book cover Comparative Pathophysiology of Circulatory Disturbances

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 22))

Abstract

Coronary heart disease is the leading cause of death in the United States and is currently responsible for over 600,000 deaths per year (1). The average risk of developing a myocardial infarction before age 60 for an apparently healthy man is approximately one in five. In addition the acute mortality following an initial myocardial infarction is about 35% with most of these acute fatalities occurring within 3 hours of onset of symptoms. It is thus evident that strategy in coping with this disease must go beyond treatment and must deal with primary prevention.

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  1. Department of Medical Pharmacology, Hoffmann-LaRoche Inc., Nutley, New Jersey, USA

    Arthur S. Leon M.S., M.D.

  2. Special Treatment Unit, Newark Beth Israel Medical Cent., USA

    Arthur S. Leon M.S., M.D.

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  1. Arthur S. Leon M.S., M.D.
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  1. Department of Pathology, University of California at San Diego, La Jolla, California, USA

    Colin M. Bloor

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Leon, A.S. (1972). Comparative Cardiovascular Adaptation to Exercise in Animals and Man and its Relevance to Coronary Heart Disease. In: Bloor, C.M. (eds) Comparative Pathophysiology of Circulatory Disturbances. Advances in Experimental Medicine and Biology, vol 22. Springer, New York, NY. https://doi.org/10.1007/978-1-4684-3213-8_10

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