In Vitro Fixation and Degradation of Radioactive Endotoxin by the RES of BCG-Treated Mice

  • L. Chedid
  • C. Rousselot
  • F. Parant
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 15)


It is well established by blood clearance experiments that treatment by BCG stimulates the RES and increases the resistance to tumors (1,2) and various bacterial (3,4) or viral (5) infections. However, paradoxically, this same treatment renders the host more susceptible to the lethal effect of endotoxins (6,7).


Lead Acetate Blood Clearance Bacterial Endotoxin Opsonizing Activity Spleen Extract 
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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • L. Chedid
    • 1
  • C. Rousselot
    • 1
  • F. Parant
    • 1
  1. 1.Centre National de la Recherche ScientifiqueParisFrance

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