Abstract
Because of the clinical and epidemiological evidence that group A streptococci play a major role in the pathogenesis of rheumatic fever and glomerulonephritis and the belief that these may be immunologic diseases (1), a number of investigations have centered on the in vivo distribution of or the host immunologic response to various components of these organisms after injection into experimental animals or natural infection. Studies of M protein, A and A variant cell wall carbohydrates, mucopeptide, cell membrane and cytoplasmic antigens have been made (2–6). However, there is only limited information on the degradation in vivo of whole group A streptococci after intravenous injection (7) and especially of the role of the reticuloendothelial system (RES) in this process.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Uhr, S.W., ed., The Streptococcus, Rheumatic Fever and Glomerulonephritis, The Williams and Wilkins Co., Baltimore, 1964.
Kaplan, M.H., J. Exp. Med. 107:341, 1958.
Schmidt, W.C., J. Exp. Med. 95:105, 1952.
Schmidt, W.C., in: Streptococcal Infections (M. McCarty, ed.), p. 87, Columbia University Press, New York, 1964.
Zabriskie, J.B., Advan. Immunol. 7:147, 1967.
Schwab, J.H. and R.R. Brown, J. Immunol. 101:930, 1968.
Schmidt, W.C., Manuscript in preparation.
Sellin, D., B. Heymer, Th.B. Smith, B. Bültmann, O. Haferkamp and W.C. Schmidt, Arch. Path., 90:17, 1970.
Heymer, B., H. Schäfer, O. Haferkamp, W. Schachenmayr and W.C. Schmidt, Manuscript in preparation.
Smith, Th.B., B. Heymer, O. Haferkamp und M. Böckeler, Z. med. Mikrobiol. u. Immunol., 152:288, 1966.
Wisse, E., Abstracts, 6th Int. Meeting Reticuloend. Soc., Freiburg 1970, p. 156.
Horn, R.G., et al., ibid., p. 65.
Ayoub, E.M. and M. McCarty, J. Exp. Med., 127:833, 1968.
Ayoub, E.M. and J.G. White, J. Bacteriol., 98:728, 1969.
Schwab, J.H. and S.H. Ohanian, J. Bacteriol., 94:1346, 1967.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1971 Plenum Press, New York
About this chapter
Cite this chapter
Heymer, B., Haferkamp, O., Schäfer, H., Schmidt, W.C. (1971). Fate of Streptococcal Antigens in the Reticuloendothelial System of the Mouse Liver. In: Di Luzio, N.R., Flemming, K.B.P. (eds) The Reticuloendothelial System and Immune Phenomena. Advances in Experimental Medicine and Biology, vol 15. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3204-6_17
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3204-6_17
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3206-0
Online ISBN: 978-1-4684-3204-6
eBook Packages: Springer Book Archive