Possible Participation of Serum-Complement in the Intracellular Killing of E. Coli
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Complement (c) was detected in 1889 by its bactericidal activity against gram-negative bacteria (1). In 1903 (2), it was discovered that C also had an opsonizing effect on bacteria, even if they were resistant to the bactericidal activity. Optimal opsonization was obtained when the third component of C was activated and attached to the bacterial surface (3) whereas for the bactericidal activity all nine components were required (4,5,6).
KeywordsBactericidal Activity Cover Slip Viable Bacterium Bacterial Surface Intracellular Killing
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