Abstract
The kininogenase from rat urine has the properties of a trypsin-like enzyme, as determined with the help of synthetic substrates or competitive inhibitors (Mares-Guia and Diniz, 1967). The work done previously was carried out with a partially purified preparation of high specific activity. The purification procedure will now be described, as well as the behavior of the enzyme in the presence of specific reagents for the trypsin active center.
This work was supported by a Grant from the University of Minas Gerais Research Council and by grants from the National Research Council, CNPq, (TC-8279, TC-9421).
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Mares-Guia, M., Silva, E., Diniz, C.R. (1970). Partial Purification of Rat Urinary Kininogenase and its Reactions with Active Center Reagents of Trypsin. In: Sicuteri, F., e Silva, M.R., Back, N. (eds) Bradykinin and Related Kinins. Advances in Experimental Medicine and Biology, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3198-8_9
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DOI: https://doi.org/10.1007/978-1-4684-3198-8_9
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