Eledoisin and Fibrinolysis in Man
Rapid administration (5 seconds) of 2 μg of eledoisin into the humeral artery, and determination of the fibrinolytic activity and the rate of the proactivator in the returning venous blood of this limb, both before and after the injection.
Slow intravenous administration of 2 μg of eledoisin and determination of the fibrinolytic activity of the venous blood before and after the injection.
Slow intra-arterial administration of eledoisin in the dose of 2. 5 μg per minute for a space of 20 minutes and determination of the fibrinolytic activity in the returning venous blood and the quantity of the proactivator before and during the injection.
Addition of eledoisin in different doses (0. 5, 1, 1. 5, 2 μg) in samples of blood (4 ml.) and study of the haematic fibrinolytic activity “in vitro”.
KeywordsVenous Blood Fibrinolytic Activity Circulatory Disease Humeral Artery Rapid Administration
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