Abstract
In pathophysiology of different shock-models kinins have often been considered as the essential factor of circulatory reactions (1, 2, 3, 14, 15). Kinins could as well be found in injuries as in edemas of extremities (4). In corresponding conditions the pro-teaseinhibitor Trasylol was given with good results, under the assumption that the kinin-formation is inhibited by this drug (5, 6, 13).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
BERALDO, W.T. Formation of Bradykinin in Anaphylactic and Peptone Shock Amer. J. Physiol. 163/283/1950
BROCKLEHURST, W.E., S.C. LAHIRI The Production of Bradykinin in Anaphylaxis J. Physiol. 160/15/1962
DAWSON, W., M.S. STARR, G.B. WEST Inhibition of Anaphylaktic Shock in the Rat by Antihistamines and Ascorbic Acid BR. J. Pharmac.Chemother. 27/249/1966
EDERY, H., G.P. LEWIS Kinin-Forming Activity and Histamine in Lymph after Tissue injury J. Physiol. 169/568/1963
EIGLER, F.W., W. STOCK Verminderung des postischämischen Extremitätenödems an der Ratte durch einen Proteinasehemmer Klin.Wschr. 46/1283/1968
EIGLER, F.W., W. STOCK Wirkung eines Proteinaseninhibitors auf das Tourniquet-Syndrom der Ratte 1.: Beeinflussung des postischämischen Ödems in Abhängigkeit von Dosis und Zeitpunkt der Trasylolgabe Z. Ges. Exp. Med. (in press)
ERDöS, E.G., J.R. WOHLER, M.I. LEVINE Blocking of the in vivo Effects of Bradykinin and Kallidin with Carboxypeptidase B J. Pharmacol. Exp. Ther. 142/327/1963
GREEFF, K., K. SCHARNAGEL, R. LüHR, H. STROBACH Die Abnahme des Kininogen-Gehaltes des Plasmas beim toxischen anaphylaktischen und anaphylak-tiden Schock Naunyn-Schmiedbergs Arch. Exp. Path. u. Pharm. 253/235/1966
HABERMANN, E. Probleme der Pathophysiologie des Kininsystems in: Neue Aspekte der Trasylol Therapie. Bnd.III S. 37, 1969, Hersg. G.L. Haberland, P. Matis, F.K. Schattauer Verlag Stuttgart-New York
KALLER, H. Die Beeinflussung experimentell erzeugter Ödeme durch Trasylol in: Neue Aspekte der Trasylol Therapie, Bnd. I, 1966, Hersg. R. Gross, G. Kroneberg F.K. Schattauer Verlag, Stuttgart
KALLER, H. personal communication
ROCHA E SILVA, M., A. Antonio Release of Bradykinin and the Mechanism of Production of Thermic Edema (45 C) in the Rats Paw Med. Exp. 3/371/1960
STOCK, W., F.W. EIGLER Wirkung eines Proteinaseninhibitors auf das Tourniquet-Syndrom der Ratte 2.: Verbesserung der Überlebensrate beim Tourniquet-Schock durch Trasylol Z. Ges. Exp. Med. (in press)
WERLE, E. Plasmakinine Dtsch. Med. Wschr. 92/1573/1967
WEBSTER, M.E., W.R. CLARK Significance of the Callicrein-Callidinogen System in Shock Amer. J. Physiol. 197/406/1959
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1970 Plenum Press, New York
About this chapter
Cite this chapter
Stock, W., Eigler, F.W. (1970). Indirect Evidence Against a Major Role of Kinins in Tourniquet-Shock by Use of Carboxypeptidase B. In: Sicuteri, F., e Silva, M.R., Back, N. (eds) Bradykinin and Related Kinins. Advances in Experimental Medicine and Biology, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3198-8_42
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3198-8_42
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3200-8
Online ISBN: 978-1-4684-3198-8
eBook Packages: Springer Book Archive