Skip to main content

In Vivo Investigations on the Role of the Kinin System in Tissue Injury and Shock Syndromes

  • Chapter
Bradykinin and Related Kinins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 8))

Abstract

The kinin system works well in vitro; its activation in vivo has been generally accepted. In older (7) and recent (4) reviews of a series of processes are enumerated in which the kinin system could be involved: functional hyperemia, especially of salivary glands, reactions to heat and to local injury, antidromic vasodilatation, circulatroy shock and related phenomena, allergic reactions, carcinoid syndrome, hereditary angioneurotic edema, gouty arthritis. Today, many of earlier theories have been doubted (for review see (5)). In order to gain fundaments for further biochemical research, we tried some experiments promising clear-cut answers to the following questions.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Aarsen, P. N.: Brit. J. Pharmacol. 32, 453 (1968).

    PubMed  CAS  Google Scholar 

  2. Diniz, C. R., J. F. Carvalho, J. Ryan, M. Rocha e Silva: Nature, 192, 1194(1961).

    Google Scholar 

  3. Folk, J. E., K. A. Piez, W. R. Carrol, J. A. Gladner: J. Biol. Chem., 235, 2272(1960).

    Google Scholar 

  4. Frey, E. K., H. Kraut, E. Werle: Das Kallikrein-Kinin-system und seine Inhibitoren: Ferdinand Enke Verlag Stuttgart, 1968.

    Google Scholar 

  5. Habermann, E.: In: Neue Aspekte der Trasylol Therapie, 3, 37 (1968). F. K. Schattauer Verlag Stuttgart-New York.

    Google Scholar 

  6. Habermann, E.: In: Heffter-Heubner Hdb. exper. Pharmakol., In press.

    Google Scholar 

  7. Lewis, G. P.: Physiol. Rev., 40, 647 (1960).

    PubMed  CAS  Google Scholar 

  8. Majno, G., G. E. Palade: J. Biophys. Biochem. Cyt., 11, 571 (1961).

    Article  CAS  Google Scholar 

  9. Rocha e Silva, M., A. Antonio: Med. exper., 3, 371 (1960).

    Google Scholar 

  10. Starr, M. S., G. B. West: Brit. J. Pharmacol., 31, 178 (1967).

    PubMed  CAS  Google Scholar 

  11. Urbanitz, D., H. Wiegand, E. Habermann: Naunyn Schmiedeberg1 s Arch. Pharmakol. exp. Path., 263, 280(1969).

    Google Scholar 

  12. Urbanitz, D., H. Wiegand, E„ Habermann: Nauyn Schmiedeberg’s Arch. Pharmakol. exp. Path., In press.

    Google Scholar 

  13. Vane, J. R.: Brit. J. Pharmacol., 35, 209(1969).

    Google Scholar 

  14. Wilhelm, D. L.: Pharmacol. Rev., 14, 251 (1962).

    PubMed  CAS  Google Scholar 

  15. Yang, H. Y. T., E. G. Erdos: Nature, 215, 1402 (1967).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1970 Plenum Press, New York

About this chapter

Cite this chapter

Urbanitz, D., Sailer, R., Habermann, E. (1970). In Vivo Investigations on the Role of the Kinin System in Tissue Injury and Shock Syndromes. In: Sicuteri, F., e Silva, M.R., Back, N. (eds) Bradykinin and Related Kinins. Advances in Experimental Medicine and Biology, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3198-8_41

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-3198-8_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3200-8

  • Online ISBN: 978-1-4684-3198-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics