Activity Ratio Between Intestinal and Cardiovascular Actions of Caerulein and Related Substances in the Anaesthetized Dog

  • G. Bertaccini
  • P. Mantovani
  • G. L. Piccinin
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 8)


Caerulein, the active peptide of the Australian amphibian Hyla caerulea, is a very versatile substance which mimicics gastrin and cholecystokinin-pancreozymin activities and possesses bradykinin-like activities as well.


Gall Bladder Activity Ratio Intestinal Motility Continuous Intravenous Infusion Cardiovascular Action 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1-.
    — Erspamer, V., Bertaccini, G., De Caro, G., Endean, R., and Impicciatore, M.: Pharmacological actions of caerulein. Experientia 23, 702 (1967).PubMedCrossRefGoogle Scholar
  2. 2-.
    — Bertaccini, G., De Caro, G., Endean, R., Erspamer, V. and Impicciatore, M.: The actions of caerulein on the smooth muscle of the gastrointestinal tract and the gall bladder. Br. J. Pharmac. 34, 291 (1968).Google Scholar
  3. 3-.
    — Anastasi, A., Bernardi, L., Bertaccini, G., Bosisio, G., Be Castiglione, R., Erspamer, V., Goffredo, O. and Impicciatore, M.: Synthetic peptides related to caerulein, Experientia, 24, 771 (1968).PubMedCrossRefGoogle Scholar
  4. 4-.
    — Bertaccini, G.: Pharmacological activity of some caerulein-like peptides. Proc. joint meet. Ital. Brit. Pharmac. Soc. 1968.Google Scholar
  5. 5-.
    — Logan, C.J.H. and Connell, A.M.: The effect of a synthetic gastrin-like pentapeptide (I.C.I.50,123) on intestinal motility in man. The Lancet i, 996 (1966).CrossRefGoogle Scholar
  6. 6-.
    — Kock, N.G., Hultén, L. and Leandoer, L.: A study of the motility in different parts of the human colon. Scand. J. Gastroenter. 3, 163 (1968).CrossRefGoogle Scholar
  7. 7-.
    — Shehadeh, Z., Price, W.E. and Jacobson, E.D.: Effects of vasoactive agents on intestinal blood flow and motility in the dog. Am. J. Physiol. 216, 386 (1969).PubMedGoogle Scholar
  8. 8-.
    — Borigotti, L. and Glasser, A.: Comparative effects of caerulein, pancreozymin and secretin on pancreatic blood flow. Experientia 24, 806 (1968).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • G. Bertaccini
    • 1
  • P. Mantovani
    • 1
  • G. L. Piccinin
    • 1
  1. 1.Institute of PharmacologyUniversity of ParmaParmaItaly

Personalised recommendations