Abstract
During the course of an immune response, studied by immuno-histochemical techniques, specific antibody has been shown to make its appearance in germinal centers of lymnh nodes of the rabbit [1] and in germinal centers of the spleen in the chicken [2]. Using the same technique, Ortega and Mellors [3] demonstrated the presence of immunoglobulins in the germinal centers of human lymph nodes and spleen, the variability of the pattern of immunoglobulin localization has made interpretation of these findings difficult. A comparison has therefore been made, by using the fluorescent antibody technique, between the cellular localization of chicken 19S and 7S immunoglobulins and the cellular immune response following injection of a soluble protein antigen, human serum albumin (HSA).
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References
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© 1969 Plenum Press
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French, V.I., Wilkinson, P.C., White, R.G. (1969). Localization by Immunofluorescence of 19S and 7S Immunoglobulin in the Lymphoid Tissue of the Chicken and its Relation to Specific Antibody Production. In: Fiore-Donati, L., Hanna, M.G. (eds) Lymphatic Tissue and Germinal Centers in Immune Response. Advances in Experimental Medicine and Biology, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3192-6_23
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DOI: https://doi.org/10.1007/978-1-4684-3192-6_23
Publisher Name: Springer, Boston, MA
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