Abstract
Cephazolin sodium is a semi-synthetic cephalosporin antibiotic given by the intramuscular or intravenous route. Peak serum levels of 38 mcg/ml have been obtained following an intramuscular dose of 500 mg. of cephazolin, recordable serum levels persisting for up to eight hours later. Approximately 60-80% of an intramuscular dose is excreted in the urine in the biologically active form in the first six hours. Urine levels of 1000 mcg/ml have been recorded following a single 500 mg. intramuscular dose.
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References
Leigh, D.A. & Williams, J.D. (1964). Method for the detection of significant bacteriuria in large groups of patients. J. Clin. Path., 17: 498
Stokes, E.J. (1968). Clinical Bacteriology, 3rd Edition, p. 179. London. Arnold.
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© 1976 Plenum Press, New York
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Rimmer, D.M.D. (1976). Cephazolin Sodium — An in Vivo and in Vitro Evaluation of 100 Patients with Urinary Tract Infections in a District General Hospital. In: Williams, J.D., Geddes, A.M. (eds) Penicillins and Cephalosporins. Chemotherapy, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3126-1_49
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DOI: https://doi.org/10.1007/978-1-4684-3126-1_49
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3128-5
Online ISBN: 978-1-4684-3126-1
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