Abstract
The determination of concentrations of free isoniazid (INH) in the blood of patients treated for tuberculosis has not yet become part of routine examination procedures; for the last 15 years, this test has nevertheless greatly helped to gain a deeper knowledge of the 2 classes of slow and rapid inactivators of isoniazid into which humans are divided, the distribution of these types of inactivators into various ethnical groups studied since 1960 by various authors (Armstrong, Harris, Jeanes, etc.), the genetic determinism of the phenotypes of inactivation determined by Evans.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Plenum Press, New York
About this chapter
Cite this chapter
Bergogne-Berezin, E., Modai, J. (1976). Comparative Study of the Inactivation of Isoniazid in Africans and Europeans. In: Williams, J.D., Geddes, A.M. (eds) Special Problems in Chemotherapy. Chemotherapy, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3120-9_9
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3120-9_9
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3122-3
Online ISBN: 978-1-4684-3120-9
eBook Packages: Springer Book Archive