Summary
Using a system for competence stimulation in B. subtilis six inhibitors of protein synthesis were tested through the 14C-phenyl-alanine incorporation, cell survival and competence. When a 20% mortality is produced, independently of the doses, gentamycin and lincomycin were the most active drugs. However, in absolute comparisons, tetracyclin molecules presented the maximal activity in such a sensitive biological system.
Keywords
- Minimal Salt Medium
- Competence Development
- Transfection Procedure
- Serial Dilution Technique
- Absolute Comparison
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1976 Plenum Press, New York
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Portoles, A., Espinosa, M., Garcia, E., Perez-Ureña, M.T. (1976). 14C-Phenyl-Alanine Incorporation in the Presence of Veral Antibiotics on B. subtilis Transfection. In: Williams, J.D., Geddes, A.M. (eds) Special Problems in Chemotherapy. Chemotherapy, vol 3. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3120-9_37
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DOI: https://doi.org/10.1007/978-1-4684-3120-9_37
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