Abstract
Nicotine is l-methyl-2-(3-pyridyl)pyrrolidine. It has an empirical formula C10H14N2 and a molecular weight of 162.23. Its structural formula is shown in Fig. 1, from which it will be seen that nicotine can exist as two optically active isomers, with the asymmetrical carbon atom at position 2 in the pyrrolidine ring. The natural (−) isomer has an S-configuration and is more potent that the (+)-R isomer (Barlow, 1968).
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Ryall, R.W. (1974). Nicotine. In: Simpson, L.L., Curtis, D.R. (eds) Poisons of Plant Origin. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2943-5_2
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